EFSA Compendium of Botanicals

Draft - work in progress

Mimusops elengi L.

Family:: Sapotaceae
Approval state:: Approved
Number of articles retrieved:: 370
Number of processed references:: 6

Compositions

#1: elengin #2: Alkaloids #3: Saponins #4: Tannins #5: Pentacyclic triterpene saponins (mimusin, misaponin A, 16-alpha hydroxy misaponin A) #6: Gallic acid #7: Mimusopin and mimusopsin #8: mimusopside A and B

Endpoint Studies

Genotoxicity

Composition #1: Sahu, Niranjan P., Koike, Kazuo., Jia, Zhonghua., Nikaido, Tamotsu. Minor triterpenoid saponin from Mimusops elengi. Natural Medicines, 1998, vol. 52, no. 1, p. 78–81. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

butanol
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

Elengin
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

COSY, C-NMR, FAB-MS, NOESY, HOHAHA
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

elengin

Composition #2: Katedeshmukh, R.G., Shete, R.V., Otari, K.V., Bagade, M.Y., Pattewar, A. Acute toxicity and diuretic activity of Mimusops elengi extracts. International Journal of Pharma and Bio Sciences, 2010, vol. 1, no. 3 . .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethyl acetate and water
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #3: Katedeshmukh, R.G., Shete, R.V., Otari, K.V., Bagade, M.Y., Pattewar, A. Acute toxicity and diuretic activity of Mimusops elengi extracts. International Journal of Pharma and Bio Sciences, 2010, vol. 1, no. 3 . .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #4: Katedeshmukh, R.G., Shete, R.V., Otari, K.V., Bagade, M.Y., Pattewar, A. Acute toxicity and diuretic activity of Mimusops elengi extracts. International Journal of Pharma and Bio Sciences, 2010, vol. 1, no. 3 . .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #5: Singh, Rajbir., Kachroo, Monika., Agrawal, Shyam S. Standardization of Centipeda minima, Mimusops elengi, Orchis mascula and Paeonia emodii. INDIAN JOURNAL OF TRADITIONAL KNOWLEDGE, 2009, vol. 8, no. 3, p. 338–345. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

mimusin, misaponin A, 16-alpha hydroxy misaponin A
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Pentacyclic triterpene saponins (mimusin, misaponin A, 16-alpha hydroxy misaponin A)

Composition #6: Akhtar, Nida., Ali, Mohd., Alam, Mohd. Sarwar. Gallic acid esters from the stem bark of Mimusops elengi L.. NATURAL PRODUCT RESEARCH, 2010, vol. 24, no. 10, p. 962–972. DOI: 10.1080/14786410902833989. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Gallic acid

Composition #7: SAHU, NP., KOIKE, K., JIA, ZH., NIKAIDO, T. NOVEL TRITERPENOID SAPONINS FROM MIMUSOPS ELENGI. tetrahedron, 1995, vol. 51, no. 48, p. 13435–13446. DOI: 10.1016/0040-4020(95)00879-D. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH extract partitioned between n-BuOH and H20.
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

Mimusopin and mimusopsin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Mimusopin and mimusopsin

Composition #8: Sahu, NP. Triterpenoid saponins of Mimusops elengi. PHYTOCHEMISTRY, 1996, vol. 41, no. 3, p. 883–886. DOI: 10.1016/0031-9422(95)00690-7. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petrol
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

mimusopside A and B
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

mimusopside A and B