EFSA Compendium of Botanicals

Draft - work in progress

Merremia dissecta (Jacq.) Hallier f.

Family:: Convolvulaceae
Approval state:: Approved
Number of articles retrieved:: 26
Number of processed references:: 4

Compositions

#1: Calystegine B2 in leaves and flowers #2: Tropane alkaloids #3: Pyrrolidine alkaloids #4: prunasin and prunasin malonate in leaves #5: total cyanide in seeds #6: prunasin-6´-malonate in leaves #7: p-coumaric acid in seed #8: amygdalin in seed

Endpoint Studies

Genotoxicity

Composition #1: Schimming, Thomas., Jenett-Siems, Kristina., Mann, Petra., Tofern-Reblin, Britta., Milson, Jenny., Johnson, Robert W., Deroin, Thierry., Austin, Daniel F., Eich, Eckart. Calystegines as chemotaxonomic markers in the Convolvulaceae. Phytochemistry (Elsevier), 2005, p. 469–480. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol 50%
Substance:

Calystegine B2 (RF-00004703-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Calystegine B2 in leaves and flowers

Composition #2: Jenett-Siems, K., Weigl, R., Bohm, A., Mann, P., Tofern-Reblin, B., Ott, SC., Ghomian, A., Kaloga, M., Siems, K., Witte, L., Hilker, M., Muller, F., Eich, E. Chemotaxonomy of the pantropical genus Merremia (Convolvulaceae) based on the distribution of tropane alkaloids. PHYTOCHEMISTRY, 2005, vol. 66, no. 12, p. 1448–1464. DOI: 10.1016/j.phytochem.2005.04.027. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol with further modifications
Substance:

Tropane alkaloids (RF-00000245-TOX)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tropane alkaloids

Composition #3: Jenett-Siems, K., Weigl, R., Bohm, A., Mann, P., Tofern-Reblin, B., Ott, SC., Ghomian, A., Kaloga, M., Siems, K., Witte, L., Hilker, M., Muller, F., Eich, E. Chemotaxonomy of the pantropical genus Merremia (Convolvulaceae) based on the distribution of tropane alkaloids. PHYTOCHEMISTRY, 2005, vol. 66, no. 12, p. 1448–1464. DOI: 10.1016/j.phytochem.2005.04.027. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol with further modifications
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Pyrrolidine alkaloids
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Pyrrolidine alkaloids

Composition #4: NAHRSTEDT, A., JENSEN, PS., WRAY, V. PRUNASIN-6'-MALONATE, A CYANOGENIC GLUCOSIDE FROM MERREMIA-DISSECTA. PHYTOCHEMISTRY, 1989, vol. 28, no. 2, p. 623–624. DOI: 10.1016/0031-9422(89)80064-0. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol with further modification
Substance:

prunasin (RF-00004011-PAR)
Additional substance description:

+ prunasin malonate
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

prunasin and prunasin malonate in leaves

Composition #5: NAHRSTEDT, A., SATTAR, EA., ELZALABANI, SMH. AMYGDALIN ACYL DERIVATIVES, CYANOGENIC GLYCOSIDES FROM THE SEEDS OF MERREMIA-DISSECTA. PHYTOCHEMISTRY, 1990, vol. 29, no. 4, p. 1179–1181. DOI: 10.1016/0031-9422(90)85424-E. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Cyanide (RF-00000021-CHE)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Millimole/kilogram (G070A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10
Internal remarks:

total cyanide in seeds
completed:

True

Composition #6: NAHRSTEDT, A., SATTAR, EA., ELZALABANI, SMH. AMYGDALIN ACYL DERIVATIVES, CYANOGENIC GLYCOSIDES FROM THE SEEDS OF MERREMIA-DISSECTA. PHYTOCHEMISTRY, 1990, vol. 29, no. 4, p. 1179–1181. DOI: 10.1016/0031-9422(90)85424-E. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

unspecified
Substance:

Cyanogenic glycosides (RF-00004375-PAR)
Additional substance description:

prunasin-6´-malonate
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

prunasin-6´-malonate in leaves
completed:

True

Composition #7: NAHRSTEDT, A., SATTAR, EA., ELZALABANI, SMH. AMYGDALIN ACYL DERIVATIVES, CYANOGENIC GLYCOSIDES FROM THE SEEDS OF MERREMIA-DISSECTA. PHYTOCHEMISTRY, 1990, vol. 29, no. 4, p. 1179–1181. DOI: 10.1016/0031-9422(90)85424-E. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol with further modification
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

p-coumaric acid in seed
completed:

True

Composition #8: NAHRSTEDT, A., SATTAR, EA., ELZALABANI, SMH. AMYGDALIN ACYL DERIVATIVES, CYANOGENIC GLYCOSIDES FROM THE SEEDS OF MERREMIA-DISSECTA. PHYTOCHEMISTRY, 1990, vol. 29, no. 4, p. 1179–1181. DOI: 10.1016/0031-9422(90)85424-E. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

amygdalin (RF-00003680-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

amygdalin in seed
completed:

True