EFSA Compendium of Botanicals

Draft - work in progress

Melaleuca cajuputi Powell // Melaleuca cajuputi subsp. cajuputi

Family:: Myrtaceae
Approval state:: Approved
Number of articles retrieved:: 126
Number of processed references:: 5

Compositions

#1: Myrcene in essential oil #2: 1,8-cineole in essential oil #3: Tannins in stem #4: Variability of 1.8-cineole in the essential oil of leaves #5: 1,8-Cineole in leaf essental oil #6: Eugenol in leaf #7: Methyleugenol in leaf

Endpoint Studies

Genotoxicity

Composition #1: Galle-Hoffmann, Ute., Konig, Wilfried A. Essential oils. Part 3. Additional tea tree oils from Melaleuca. deutsche apotheker zeitung, 1999, p. 59–62. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.9
Internal remarks:

Myrcene in essential oil

Composition #2: Galle-Hoffmann, Ute., Konig, Wilfried A. Essential oils. Part 3. Additional tea tree oils from Melaleuca. deutsche apotheker zeitung, 1999, p. 59–62. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

65.2
Internal remarks:

1,8-cineole in essential oil

Composition #3: Batubara, I., Kotsuka, S., Yamauchi, K., Kuspradini, H., Mitsunaga, T., Darusman, L.K. TNF-α production inhibitory activity, phenolic, flavonoid and tannin contents of selected Indonesian medicinal plants. Research Journal of Medicinal Plant, 2012, vol. 6, no. 6, p. 406–415. DOI: 10.3923/rjmp.2012.406.415. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

expressed as amount of BSA precipitated
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

98.8
Internal remarks:

Tannins in stem

Composition #4: Susanto, M., Doran, J., Arnold, R., Rimbawanto, A. Genetic variation in growth and oil characteristics of Melaleuca cajuputi subsp cajuputi and potential for genetic improvement . journal of tropical forest science, 2003, vol. 15, no. 3, p. 469–482. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

42.7-60.2
Internal remarks:

Variability of 1.8-cineole in the essential oil of leaves

Composition #5: Silva, Cleber J., Barbosa, Luiz C. A., Maltha, Ulia R. A., Pinheiro, Antonio L., Ismail, Fyaz M. D. Comparative study of the essential oils of seven Meialeuca (Myrtaceae) species grown in Brazil. FLAVOUR AND FRAGRANCE JOURNAL, 2007, vol. 22, no. 6, p. 474–478. DOI: 10.1002/ffj.1823. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydro distillation, Clevenger-type
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

43.7
Internal remarks:

1,8-Cineole in leaf essental oil

Composition #6: Jajaei, S. M., Daud, W. R. W., Markom, M., Zakaria, Z., Lo Presti, M., Costa, Rosaria., Mondello, L., Santi, Luca. Extraction of Melaleuca cajuputi Using Supercritical Fluid Extraction and Solvent Extraction. JOURNAL OF ESSENTIAL OIL RESEARCH, 2010, vol. 22, no. 3, p. 205–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane, Supercritic Fluid Extraction
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.4-1.2
Internal remarks:

Eugenol in leaf

Composition #7: Jajaei, S. M., Daud, W. R. W., Markom, M., Zakaria, Z., Lo Presti, M., Costa, Rosaria., Mondello, L., Santi, Luca. Extraction of Melaleuca cajuputi Using Supercritical Fluid Extraction and Solvent Extraction. JOURNAL OF ESSENTIAL OIL RESEARCH, 2010, vol. 22, no. 3, p. 205–210. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane, Supercritic Fluid Extraction
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2-1.3
Internal remarks:

Methyleugenol in leaf