EFSA Compendium of Botanicals

Draft - work in progress

Camomile (as plant) // Matricaria chamomilla L. // Matricaria recutita L. // Matricaria suaveolens L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 2133
Number of processed references:: 4

Compositions

#1: Coumarins in flowers #2: Coumarins in aerial parts #3: Pulegone in essenial oil #4: Umbellifeone (Coumarin) in flower #5: Sesquiterpene lactones ( achillin, leucodin, matricarin e acetoxy achillin) in flower

Endpoint Studies

Genotoxicity

Composition #1: Reichling, Juergen., Beiderbeck, Rolf., Becker, Hans. Comparative studies on secondary products from tumors, flowers, foliage and roots of Matricaria chamomilla L. planta medica, 1979, p. 322–332. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

herniarin and umbelliferon
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins in flowers

Composition #2: Reichling, Juergen., Beiderbeck, Rolf., Becker, Hans. Comparative studies on secondary products from tumors, flowers, foliage and roots of Matricaria chamomilla L. planta medica, 1979, p. 322–332. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

herniarin and umbelliferon
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins in aerial parts

Composition #3: Graciela Malinskas, Griselda Ana., Santi, Maria Noemi., Retamar, Juan Alberto. The essential oil of Matricaria chamomilla L. (chamomile). essenze, derivati agrumari, 1985, p. 52–61. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

(+)-pulegone (RF-00003398-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.316-1.01
Internal remarks:

Pulegone in essenial oil

Composition #4: Paszkiewicz, Monika., Orlita, Aleksandra., Dziabas, Alicja., Golebiowski, Marek., Lojkowska, Ewa., Szafranek, Janusz., Malinski, Edmund., Stepnowski, Piotr. Simplex optimized LC analysis of plant coumarins and furanocoumarins. Chromatographia, 2008, p. 653–657. . [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol,water ,tetrahydrofuran
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

HPLC-DAD (F587A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Umbellifeone (Coumarin) in flower

Composition #5: Tschiggerl, Christine., Bucar, Franz. Guaianolides and Volatile Compounds in Chamomile Tea. plant foods for human nutrition (new york, ny, united states), 2012, p. 129–135. .

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

infusion solid phase extraction ,dichloromethane
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

achillin, leucodin, matricarin and acetoxyachillin
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.18
Internal remarks:

Sesquiterpene lactones ( achillin, leucodin, matricarin e acetoxy achillin) in flower