EFSA Compendium of Botanicals

Draft - work in progress

Lysimachia nummularia L.

Family:: Primulaceae
Approval state:: Approved
Number of articles retrieved:: 160
Number of processed references:: 4

Compositions

#1: Embelin in stems #2: Embelin in leaves #3: Embelin in root #4: total saponins in roots #5: total saponins in stems #6: Methyleugenol #7: Nummularoside

Endpoint Studies

Genotoxicity

Composition #1: Podolak, Irma., Strzalka, Marian. Qualitative and quantitative LC profile of embelin and rapanone in selected Lysimachia species. Chromatographia, 2008, p. 471–475. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

CHCL3
Substance:

embelin (RF-00003797-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.82
Internal remarks:

Embelin in stems

Composition #2: Podolak, Irma., Strzalka, Marian. Qualitative and quantitative LC profile of embelin and rapanone in selected Lysimachia species. Chromatographia, 2008, p. 471–475. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

CHCL3
Substance:

embelin (RF-00003797-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.68
Internal remarks:

Embelin in leaves

Composition #3: Podolak, Irma., Strzalka, Marian. Qualitative and quantitative LC profile of embelin and rapanone in selected Lysimachia species. Chromatographia, 2008, p. 471–475. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

CHCL3
Substance:

embelin (RF-00003797-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.2
Internal remarks:

Embelin in root

Composition #4: Podolak, Irma., Hubicka, Urszula., Zuromska-Witek, Barbara., Janeczko, Zbigniew., Krzek, Jan. Quantification of saponins in different plant parts of Lysimachia L. species by validated HPTLC-densitometric method. journal of planar chromatography--modern tlc, 2013, p. 248–253. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform + methanol
Substance:

Saponins (RF-00004333-PAR)
Additional substance description:

total saponins
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.26
Internal remarks:

total saponins in roots

Composition #5: Podolak, Irma., Hubicka, Urszula., Zuromska-Witek, Barbara., Janeczko, Zbigniew., Krzek, Jan. Quantification of saponins in different plant parts of Lysimachia L. species by validated HPTLC-densitometric method. journal of planar chromatography--modern tlc, 2013, p. 248–253. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform + methanol
Substance:

Saponins (RF-00004333-PAR)
Additional substance description:

total saponins
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.18
Internal remarks:

total saponins in stems

Composition #6: Demyd, A. E. Essential oils composition of moneywort (Lysimachia nummularia L.). medichna khimiya, 2014, p. 58–61. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Methyleugenol

Composition #7: Podolak, Irma., Koczurkiewicz, Paulina., Michalik, Marta., Galanty, Agnieszka., Zajdel, Pawel., Janeczko, Zbigniew. A new cytotoxic triterpene saponin from Lysimachia nummularia L.. CARBOHYDRATE RESEARCH, 2013, vol. 375, p. 16–20. DOI: 10.1016/j.carres.2013.04.005. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

CHCl3, MeOH with 0.5% Pyridine.
Substance:

pentacyclic triterpene saponins (RF-00004334-PAR)
Additional substance description:

Nummularoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR + MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Nummularoside