EFSA Compendium of Botanicals

Endpoint study #1: Yang, Bao-cheng., Peng, Tao., Zhang, Qianjun., Yin, Zhen-hua., Kang, Wenyi. alpha-Glucosidase Inhibitory Compounds of Lycopus lucidus var. hirtus. chemistry of natural compounds, 2014, vol. 50, no. 1, p. 169–171. DOI: 10.1007/s10600-014-0903-2. [DOI link]

Study relevance:

Human health
Plant part:

Live plants (as part-nature) (A0BA0)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

methanol extract; substances isolated: Primar-15-en-3-ol, betulin, betulinic acid, Oleanolic Acid, ursolic acid, 2,3-Dihydroxyolean-5,12-dien-28-oic Acid, asiatic acid
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Half maximal inhibitory concentration (CHD021EP)
Concentration unit:

Microgram/millilitre (G052A)
Effect concentration:

2.43-15.18
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

alpha-glucosidase inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

alpha-glucosidase inhibition

Lycopus lucidus Turcz. ex Benth.