EFSA Compendium of Botanicals

Draft - work in progress

Litsea glutinosa (Lour.) C.B.Rob.

Family:: Lauraceae
Approval state:: Approved
Number of articles retrieved:: 146
Number of processed references:: 7

Compositions

#1: Alkaloids (bark) #2: Alkaloids (leaves) #3: Tannins #4: Alkaloids #5: Aporphine alkaloids #6: Epoxides #7: Beta-myrcene #8: Lignans #9: Furan derivatives (butenolides) #10: Methyl eugenol #11: Myrcene

Endpoint Studies

Genotoxicity

Composition #1: Hart, N. K., Johns, S. R., Lamberton, John A., Loder, John W., Moorhouse, Anne., Sioumis, A. A., Smith, T. K. Alkaloids of several Litsea species from New Guinea. australian journal of chemistry, 1969, p. 2259–2262. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform-methanol (9 : 1)
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Total alkaloids in mark; main alkaloid: Laurolitsine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.32
Internal remarks:

Alkaloids (bark)

Composition #2: Hart, N. K., Johns, S. R., Lamberton, John A., Loder, John W., Moorhouse, Anne., Sioumis, A. A., Smith, T. K. Alkaloids of several Litsea species from New Guinea. australian journal of chemistry, 1969, p. 2259–2262. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform-methanol (9 : 1)
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

total alkaloids in leaves
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.24
Internal remarks:

Alkaloids (leaves)

Composition #3: Khatun Amina., Haque Tania., Akter Mahfuja., Akter Subarna., Jhumur Afrin., Rahman Mahmudur., Rahman Md Mahfizur. Cytotoxicity potentials of eleven Bangladeshi medicinal plants. thescientificworldjournal, 2014 . .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #4: Khatun Amina., Haque Tania., Akter Mahfuja., Akter Subarna., Jhumur Afrin., Rahman Mahmudur., Rahman Md Mahfizur. Cytotoxicity potentials of eleven Bangladeshi medicinal plants. thescientificworldjournal, 2014 . .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #5: Yang, JH., Li, L., Wang, YS., Zhao, JF., Zhang, HB., Luo, SD. Two new aporphine alkaloids from Litsea glutinosa. helvetica chimica acta, 2005, vol. 88, no. 9, p. 2523–2526. DOI: 10.1002/hlca.200590188. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

butanol
Substance:

Aporphine alkaloids (RF-00010806-PAR)
Additional substance description:

litseglutine A and B, boldine, laurolitsine
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Aporphine alkaloids

Composition #6: Chowdhury, Jasim Uddin., Bhuiyan, Md. Nazrul Islam., Nandi, Nemai Chandra. Aromatic plants of Bangladesh: Essential oils of leaves and fruits of Litsea glutinosa (Lour.) C.B. Robinson . bangladesh journal of botany, 2008, vol. 37, no. 1, p. 81–83. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

epoxides (RF-00010829-PAR)
Additional substance description:

Diepi-.α-cedrene epoxide
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.79
Internal remarks:

Epoxides

Composition #7: Chowdhury, Jasim Uddin., Bhuiyan, Md. Nazrul Islam., Nandi, Nemai Chandra. Aromatic plants of Bangladesh: Essential oils of leaves and fruits of Litsea glutinosa (Lour.) C.B. Robinson . bangladesh journal of botany, 2008, vol. 37, no. 1, p. 81–83. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5
Internal remarks:

Beta-myrcene

Composition #8: Pan, Jian-Yu., Zhang, Si., Wu, Jun., Li, Qing-Xin., Xiao, Zhi-Hui. Litseaglutinan A and Lignans from Litsea glutinosa. helvetica chimica acta, 2010, vol. 93, no. 5, p. 951–957. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

abscisic acid derivative (litseaglutinan A) and arylnaphthalene-type lignan; + 9 known lignans
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans

Composition #9: Agrawal, Nisha., Pareek, Deepika., Dobhal, Sonal., Sharma, Mahesh C., Joshi, Yogesh C., Dobhal, Mahabeer P. Butanolides from Methanolic Extract of Litsea glutinosa. chemistry & biodiversity, 2013, vol. 10, no. 3, p. 394–400. DOI: 10.1002/cbdv.201100300. [DOI link]

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol extract of heartwood
Substance:

furan derivatives (RF-00004396-PAR)
Additional substance description:

Butenolides: (3R,4S,5S)-2-hexadecyl-3-hydroxy-4-methylbutanolide, litsealactones C, D and G
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Furan derivatives (butenolides)

Composition #10: Son, Le C., Dai, Do N., Thang, Tran D., Huyen, Duong D., Ogunwande, Isiaka A. Analysis of the Essential Oils from Five Vietnamese Litsea Species (Lauraceae) . journal of essential oil bearing plants, 2014, vol. 17, no. 5, p. 960–971. DOI: 10.1080/0972060X.2014.935068. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.2
Internal remarks:

Methyl eugenol

Composition #11: Son, Le C., Dai, Do N., Thang, Tran D., Huyen, Duong D., Ogunwande, Isiaka A. Analysis of the Essential Oils from Five Vietnamese Litsea Species (Lauraceae) . journal of essential oil bearing plants, 2014, vol. 17, no. 5, p. 960–971. DOI: 10.1080/0972060X.2014.935068. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1
Internal remarks:

Myrcene