EFSA Compendium of Botanicals

Draft - work in progress

Lilium candidum L.

Family:: Liliaceae
Approval state:: Approved
Number of articles retrieved:: 235
Number of processed references:: 5

Compositions

#1: cis-antheraxathin (lutein-epoxide) #2: Lilaline (pyrrolidine alkaloid) in the aerial part #3: spirostanol saponins #4: Furostanol saponins #5: Two spirostanol saponins #6: Jatropham (alkaloid) #7: Etioline (steroidal alkaloid) in bulb

Endpoint Studies

Genotoxicity

Composition #1: Toth, Gyula., Kajtar, Judit., Molnar, Peter., Szabolcs, Jozsef. The stereochemistry of natural 'cis-antheraxanthin'. acta chimica academiae scientiarum hungaricae, 1978, p. 359–361. .

Language:

English (en)
Plant part:

Pollen-related (as part-nature) (A0ESK)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

epoxides (RF-00010829-PAR)
Additional substance description:

cis-antheraxathin
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cis-antheraxathin (lutein-epoxide)

Composition #2: Haladova, Maria., Buckova, Anna., Eisenreichova, Eva., Tomko, Jozef., Uhrin, Dusan. Constituents of Lilium candidum L. acta facultatis pharmaceuticae universitatis comenianae, 1991, p. 151–174. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Lilaline
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lilaline (pyrrolidine alkaloid) in the aerial part

Composition #3: Mimaki, Y., Satou, T., Kuroda, M., Sashida, Y., Hatakeyama, Y. Steroidal saponins from the bulbs of Lilium candidum. PHYTOCHEMISTRY, 1999, vol. 51, no. 4, p. 567–573. DOI: 10.1016/S0031-9422(99)00022-9. [DOI link]

Language:

English (en)
Plant part:

Bulb / clove (as part-nature) (A067A)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Steroidal spirostane saponins Steroidal spirostane saponins (RF-00004321-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

spirostanol saponins

Composition #4: Mimaki, Y., Satou, T., Kuroda, M., Sashida, Y., Hatakeyama, Y. Steroidal saponins from the bulbs of Lilium candidum. PHYTOCHEMISTRY, 1999, vol. 51, no. 4, p. 567–573. DOI: 10.1016/S0031-9422(99)00022-9. [DOI link]

Language:

English (en)
Plant part:

Bulb / clove (as part-nature) (A067A)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

steroidal furostan saponins steroidal furostan saponins (RF-00004397-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Furostanol saponins

Composition #5: Vachalkova, A., Eisenreichova, E., Haladova, M., Mucaji, P., Jozova, B., Novotny, L. Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L. . neoplasma, 2000, vol. 47, no. 5, p. 313–318. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Steroidal spirostane saponins Steroidal spirostane saponins (RF-00004321-PAR)
Additional substance description:

two spiristanol saponins
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Two spirostanol saponins

Composition #6: Vachalkova, A., Eisenreichova, E., Haladova, M., Mucaji, P., Jozova, B., Novotny, L. Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L. . neoplasma, 2000, vol. 47, no. 5, p. 313–318. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Jatropham
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Jatropham (alkaloid)

Composition #7: Erdogan, I., Sener, B., Atta-ur-Rahman. Etioline, a steroidal alkaloid from Lilium candidum L.. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2001, vol. 29, no. 5, p. 535–536. DOI: 10.1016/S0305-1978(00)00075-2. [DOI link]

Language:

English (en)
Plant part:

Bulb / clove (as part-nature) (A067A)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

EtOH
Substance:

Steroidal alkaloids (RF-00004336-PAR)
Additional substance description:

Etioline
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Etioline (steroidal alkaloid) in bulb