EFSA
ecomole
vscht
  2. Garden cress (as plant) // Lepidium sativum L.

Garden cress (as plant) // Lepidium sativum L.

Family:
Brassicaceae
Approval state:
Approved
Number of articles retrieved:
2463
Number of processed references:
3
Compositions
#1: Glucotropaeolin (glucosinolate) #2: Alkaloids in cress #3: Coumarins in cress
Endpoint Studies
Genotoxicity
#1: The findings of the present study indicated that administration of BaP induces a significant oxidative stress and genotoxicity in epididymal sperm and testis which are associated with DNA damage and spermatogenetic dysfunction.
Composition #1: Kassie, F., Rabot, S., Uhl, M., Huber, W., Qin, HM., Helma, C., Schulte-Hermann, R., Knasmuller, S. Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions. CARCINOGENESIS, 2002, vol. 23, no. 7, p. 1155–1161. DOI: 10.1093/carcin/23.7.1155. [DOI link]
Composition #2: Nebo, Liliane., Varela, Rosa M., Molinillo, Jose M. G., Sampaio, Olivia M., Severino, Vanessa G. P., Cazal, Cristiane M., das Gracas Fernandes da Silva, Maria Fatima., Fernandes, Joao B., Macias, Francisco A. Phytotoxicity of alkaloids, coumarins and flavonoids isolated from 11 species belonging to the Rutaceae and Meliaceae families. PHYTOCHEMISTRY LETTERS, 2014, vol. 8, p. 226–232. DOI: 10.1016/j.phytol.2014.02.010. [DOI link]
Composition #3: Nebo, Liliane., Varela, Rosa M., Molinillo, Jose M. G., Sampaio, Olivia M., Severino, Vanessa G. P., Cazal, Cristiane M., das Gracas Fernandes da Silva, Maria Fatima., Fernandes, Joao B., Macias, Francisco A. Phytotoxicity of alkaloids, coumarins and flavonoids isolated from 11 species belonging to the Rutaceae and Meliaceae families. PHYTOCHEMISTRY LETTERS, 2014, vol. 8, p. 226–232. DOI: 10.1016/j.phytol.2014.02.010. [DOI link]
Genotox #1: Hassan, A. M., Alam, S. S., Abdel-Aziem, S. H., Ahmed, K. A. Benzo-​a-​pyrene induced genotoxicity and cytotoxicity in germ cells of mice: intervention of radish and cress. Journal of Genetic Engineering and Biotechnology, 2011, p. 65–72. .