EFSA Compendium of Botanicals

Draft - work in progress

Lepidium draba L. // Cardaria draba (L.) Desv.

Family:: Brassicaceae
Approval state:: Approved
Number of articles retrieved:: 171
Number of processed references:: 5

Compositions

#1: Two alkaloids in live plants #2: allyl-methylthiobutyl-glucosinolate #3: butyl-glucosinolate #4: 4-methylthiobutyl-glucosinolate #5: but-3-enyl-glucosinolate #6: l-methylpropyl-glucosinolate #7: Erucic acid #8: Oxalic acid #9: L-prolinium 4-(methylsulfinyl)butyl glucosinolate and sinalbin from flowering tops #10: Glucoraphanin in leaves

Endpoint Studies

Genotoxicity

Composition #1: Potapov, V. M. Phytochemical study of Cardaria draba. meditsinskii zhurnal uzbekistana, 1976, p. 61–62. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Two alkaloids in live plants

Composition #2: Hasapis, Xenophon., MacLeod, Alexander J., Moreau, Marie. Glucosinolates of nine Cruciferae and two Capparaceae species. Phytochemistry (Elsevier), 1981, p. 2355–2358. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

allyl-methylthiobutyl-glucosinolate
Analytical method code:

GC-MS (F046A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13
Internal remarks:

allyl-methylthiobutyl-glucosinolate

Composition #3: Hasapis, Xenophon., MacLeod, Alexander J., Moreau, Marie. Glucosinolates of nine Cruciferae and two Capparaceae species. Phytochemistry (Elsevier), 1981, p. 2355–2358. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

butyl-glucosinolate
Analytical method code:

GC-MS (F046A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

81
Internal remarks:

butyl-glucosinolate

Composition #4: Hasapis, Xenophon., MacLeod, Alexander J., Moreau, Marie. Glucosinolates of nine Cruciferae and two Capparaceae species. Phytochemistry (Elsevier), 1981, p. 2355–2358. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

4-methylthiobutyl-glucosinolate
Analytical method code:

GC-MS (F046A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

618
Internal remarks:

4-methylthiobutyl-glucosinolate

Composition #5: Hasapis, Xenophon., MacLeod, Alexander J., Moreau, Marie. Glucosinolates of nine Cruciferae and two Capparaceae species. Phytochemistry (Elsevier), 1981, p. 2355–2358. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

but-3-enyl-glucosinolate
Analytical method code:

GC-MS (F046A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

69
Internal remarks:

but-3-enyl-glucosinolate

Composition #6: Hasapis, Xenophon., MacLeod, Alexander J., Moreau, Marie. Glucosinolates of nine Cruciferae and two Capparaceae species. Phytochemistry (Elsevier), 1981, p. 2355–2358. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Hexane
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

l-methylpropyl-glucosinolate
Analytical method code:

GC-MS (F046A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

306
Internal remarks:

l-methylpropyl-glucosinolate

Composition #7: Guil, J. L., Rodriguez-Garcia, I., Torija, E. Nutritional and toxic factors in selected wild edible plants. plant foods for human nutrition (dordrecht, netherlands), 1997, p. 99–107. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetyl chloride and methanol
Substance:

Erucic acid (RF-00000249-NTR)
Analytical method code:

Gaschromatography (GC) (F037A)
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.23
Internal remarks:

Erucic acid

Composition #8: Guil, J. L., Rodriguez-Garcia, I., Torija, E. Nutritional and toxic factors in selected wild edible plants. plant foods for human nutrition (dordrecht, netherlands), 1997, p. 99–107. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

oxalic acid (RF-00000356-NTR)
Analytical method code:

Gaschromatography (GC) (F037A)
Value (concentration, content):

traces
Internal remarks:

Oxalic acid

Composition #9: Frechard, Antoine., Fabre, Nicolas., Hannedouche, Sebastien., Fouraste, Isabelle. Glucosinolates from Cardaria draba. Fitoterapia, 2002, p. 177–178. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

L-prolinium 4-(methylsulfinyl)butyl glucosinolate, sinalbin
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

L-prolinium 4-(methylsulfinyl)butyl glucosinolate and sinalbin from flowering tops

Composition #10: Powell, Erin E., Hill, Gordon A., Juurlink, Bernhard H. J., Carrier, D. Julie. Glucoraphanin extraction from Cardaria draba: Part 1. Optimization of batch extraction. Journal of Chemical Technology and Biotechnology, 2005, p. 985–991. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

glucoraphanin (RF-00010874-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

30.0
Internal remarks:

Glucoraphanin in leaves