EFSA Compendium of Botanicals

Draft - work in progress

Kadsura heteroclita (Roxb.) Craib

Family:: Schisandraceae
Approval state:: Approved
Number of articles retrieved:: 85
Number of processed references:: 5

Compositions

#1: Lignans #2: D-Epigalbacin #3: 1,8-cineole #4: Methyleugenol #5: Schisanlignone A #6: Kadsurin

Endpoint Studies

Genotoxicity

Composition #1: Wang, W., Liu, JZ., Liu, RX., Xu, ZR., Yang, M., Wang, WX., Liu, P., Sabia, G., Wang, XM., Guo, D. Four new lignans from the stems of Kadsura heteroclita. PLANTA MEDICA, 2006, vol. 72, no. 3, p. 284–288. DOI: 10.1055/s-2005-916213. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

Heteroclitalignans A to D, kadsurarin, kadsulignan E
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans

Composition #2: Wang, Wei., Liu, Jinzhi., Yang, Min., Sun, Jianghao., Wang, Xiaoming., Liu, Rongxia., Guo, Dean. Simultaneous determination, of six major constituents in the stems of Kadsura heteroclita by LC-DAD. CHROMATOGRAPHIA, 2006, vol. 64, no. 5-6, p. 297–302. DOI: 10.1365/s10337-006-0031-7. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ACN:H2O (8:2)
Substance:

D-epigalbacin (RF-00011390-PAR)
Analytical method code:

HPLC-UV (F021A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<= 0.74
Internal remarks:

D-Epigalbacin

Composition #3: Li, He Qin., Bai, Chun Qi., Chu, Sha Sha., Zhou, Ligang., Du, Shu Shan., Liu, Zhi Long., Liu, Qi Zhi. Chemical composition and toxicities of the essential oil derived from Kadsura heteroclita stems against Sitophilus zeamais and Meloidogyne incognita . journal of medicinal plants research, 2011, vol. 5, no. 19, p. 4943–4948. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.25
Internal remarks:

1,8-cineole

Composition #4: Li, He Qin., Bai, Chun Qi., Chu, Sha Sha., Zhou, Ligang., Du, Shu Shan., Liu, Zhi Long., Liu, Qi Zhi. Chemical composition and toxicities of the essential oil derived from Kadsura heteroclita stems against Sitophilus zeamais and Meloidogyne incognita . journal of medicinal plants research, 2011, vol. 5, no. 19, p. 4943–4948. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.05
Internal remarks:

Methyleugenol

Composition #5: Chen Min., Luo You-Ping., Zou Yan-Lin., Lang Ling-Hu., Chen Dao-Feng. Heteroclitins R-S: new dibenzocylooctadiene lignans from Kadsura heteroclita. CHINESE JOURNAL OF NATURAL MEDICINES, 2014, vol. 12, no. 9, p. 689–692. DOI: 10.3724/SP.J.1009.2014.00689. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

Schisanlignone A
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Schisanlignone A

Composition #6: YANG, XW., HATTORI, M., NAMBA, T., CHEN, DF., XU, GJ. ANTI-LIPID PEROXIDATIVE EFFECT OF AN EXTRACT OF THE STEMS OF KADSURA-HETEROCLITA AND ITS MAJOR CONSTITUENT, KADSURIN, IN MICE. CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, vol. 40, no. 2, p. 406–409. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

kadsurin (RF-00011064-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Kadsurin