Draft - work in progress
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- Ipomoea purpurea (L.) Roth. // Pharbitis purpurea Asch. in Schweinf.
Ipomoea purpurea (L.) Roth. // Pharbitis purpurea Asch. in Schweinf.
- Family:
- Convolvulaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 799
- Number of processed references:
- 4
Composition #1: Hylin, John W., Watson, Donald P. Ergoline alkaloids in tropical wood roses. science (washington, dc, united states), 1965, p. 499–500. .
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Ether
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Substance:
ergoline alkaloids (RF-00004355-PAR)
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Result unit:
Milligram/gram (G060A)
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Result expression:
Whole weight (B001A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.423-0.813
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Internal remarks:
Ergoline alkaloids
Composition #2: Genest, K. A direct densitometric method on thin-layer plates for the determination of lysergic acid amide, isolysergic acid amide, and clavine alkaloids in morning glory seeds. journal of chromatography, 1965, p. 531–539. .
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
unspecified
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Substance:
lysergic acid (RF-00003915-PAR)
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Additional substance description:
lysergic acid and derivatives: Lysergic acid amide and isolysergic acid amide
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Lysergic acid
Composition #3: Wang, Jin-Lan., Hua, Zhun., Zhao, Bao-Ying., Tang, Wan-Xia., Zhang, Shu-Jun. Studies on the chemical constituents of Pharbitis purpurea .. zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2010, vol. 33, no. 10, p. 1571–4. .
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Plant part:
Unspecified (A07XD)
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Additional extraction description:
unspecified
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Substance:
umbelliferone (RF-00004096-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Umbelliferone
Genotox #1: Friedman, Mendel., Henika, Philip R. Mutagenicity of toxic weed seeds in the Ames test: jimson weed (Datura stramonium), velvetleaf (Abutilon theophrasti), morning glory (Ipomoea spp.), and sicklepod (Cassia obtusifolia). journal of agricultural and food chemistry, 1991, p. 494–501. .
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Study category:
Mutagenicity
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Type of toxicological test:
bacterial reverse mutation assay (CHD028TT)
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Tested organism:
Salmonella typhimurium (as organism) (A0CPZ)
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Strain of test organism:
TA 102 (CHD025ST)
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Exogenous metabolic activation applied:
with and without
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Endpoint measured:
gene mutation
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Remarks on genotox study:
Seed extract causes mutagenicity (methanol extract - the most potent to cause mutagenicity)
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Internal remarks:
Mutagenicity
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Internal ID:
CAPLUS_1991:120425
