EFSA Compendium of Botanicals

Draft - work in progress

Illicium lanceolatum A.C. Sm.

Family:: Schisandraceae
Approval state:: Approved
Number of articles retrieved:: 51
Number of processed references:: 5

Endpoint Studies

Genotoxicity

Composition #1: Howes, Melanie-Jayne R., Kite, Geoffrey C., Simmonds, Monique S. J. Distinguishing Chinese Star Anise from Japanese Star Anise Using Thermal Desorption - Gas Chromatography - Mass Spectrometry. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, vol. 57, no. 13, p. 5783–5789. DOI: 10.1021/jf9009153. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myristicin (RF-00003941-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

TD-GC-MS
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.1
Internal remarks:

myristicin

Composition #2: Howes, Melanie-Jayne R., Kite, Geoffrey C., Simmonds, Monique S. J. Distinguishing Chinese Star Anise from Japanese Star Anise Using Thermal Desorption - Gas Chromatography - Mass Spectrometry. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, vol. 57, no. 13, p. 5783–5789. DOI: 10.1021/jf9009153. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

TD-GC-MS
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=10.3
Internal remarks:

elemicin

Composition #3: Howes, Melanie-Jayne R., Kite, Geoffrey C., Simmonds, Monique S. J. Distinguishing Chinese Star Anise from Japanese Star Anise Using Thermal Desorption - Gas Chromatography - Mass Spectrometry. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, vol. 57, no. 13, p. 5783–5789. DOI: 10.1021/jf9009153. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

TD-GC-MS
Result unit:

Percent (G138A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.1-36.6
Internal remarks:

1,8-cineole

Composition #4: Liang, Jie., Huang, Baokang., Wang, Guowei. Chemical composition, antinociceptive and anti-inflammatory properties of essential oil from the roots of Illicium lanceolatum . natural product research, 2012, vol. 26, no. 18, p. 1712–1714. DOI: 10.1080/14786419.2011.603318. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methylisoeugenol (RF-00003493-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

11.19
Internal remarks:

Methylisoeugenol

Composition #5: Liang, Jie., Huang, Baokang., Wang, Guowei. Chemical composition, antinociceptive and anti-inflammatory properties of essential oil from the roots of Illicium lanceolatum . natural product research, 2012, vol. 26, no. 18, p. 1712–1714. DOI: 10.1080/14786419.2011.603318. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myristicin (RF-00003941-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

17.63
Internal remarks:

Myristicin

Composition #6: Liang, Jie., Huang, Baokang., Wang, Guowei. Chemical composition, antinociceptive and anti-inflammatory properties of essential oil from the roots of Illicium lanceolatum . natural product research, 2012, vol. 26, no. 18, p. 1712–1714. DOI: 10.1080/14786419.2011.603318. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

asarone (RF-00003698-PAR)
Additional substance description:

alpha-asarone
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

17.23
Internal remarks:

Alpha-asarone

Composition #7: Liang, Jie., Huang, Baokang., Wang, Guowei. Chemical composition, antinociceptive and anti-inflammatory properties of essential oil from the roots of Illicium lanceolatum . natural product research, 2012, vol. 26, no. 18, p. 1712–1714. DOI: 10.1080/14786419.2011.603318. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

apiole (RF-00003690-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.82
Internal remarks:

Apiole

Composition #8: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.78
Internal remarks:

1,8-cineole in leaves

Composition #9: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

24.47
Internal remarks:

1,8-cineole in fruits

Composition #10: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.41
Internal remarks:

Camphor in leaves

Composition #11: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

apiole (RF-00003690-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.02
Internal remarks:

Apiole in fruits

Composition #12: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.93
Internal remarks:

Elemicin in leaves

Composition #13: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

asarone (RF-00003698-PAR)
Additional substance description:

alpha-asarone
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

17.23
Internal remarks:

Alpha-asarone in roots

Composition #14: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

beta-asarone (RF-00003708-PAR)
Additional substance description:

Cis-beta-asarone
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.14
Internal remarks:

Cis-beta-asarone in roots

Composition #15: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myristicin (RF-00003941-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.82
Internal remarks:

Myristicin in fruits

Composition #16: Huang, Baokang., Liang, Jie., Wang, Guowei., Qin, Luping. Comparison of the Volatile Components of Illicium verum and I. lanceolatum from East China . journal of essential oil bearing plants, 2012, vol. 15, no. 3, p. 467–475. DOI: 10.1080/0972060X.2012.10644074. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

apiole (RF-00003690-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.82
Internal remarks:

Apiole in roots

Composition #17: Mathon, Caroline., Bongard, Benjamin., Duret, Monique., Ortelli, Didier., Christen, Philippe., Bieri, Stefan. Analysis of the neurotoxin anisatin in star anise by LC-MS/MS. EXPOSURE & RISK ASSESSMENT, 2013, vol. 30, no. 9, p. 1598–1605. DOI: 10.1080/19440049.2013.804955. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

cyclohexane
Substance:

anisatin (RF-00003685-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Result unit:

Milligram/kilogram (G061A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

566
Internal remarks:

anisatin

Composition #18: Gui, Xuan., Wang, Guowei., Zhang, Naidan., Huang, Baokang. New phenylpropanoid and other compounds from Illicium lanceolatum with inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. FITOTERAPIA, 2014, vol. 95, p. 51–57. DOI: 10.1016/j.fitote.2014.02.015. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% ethanol
Substance:

phenylpropanoids (RF-00004367-PAR)
Additional substance description:

1-ally- 3,5-dimethoxyphenol
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, FAB-MS, HRESIMS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Phenylpropanoids (1-ally-3,5-dimethoxyphenol)

Composition #19: Gui, Xuan., Wang, Guowei., Zhang, Naidan., Huang, Baokang. New phenylpropanoid and other compounds from Illicium lanceolatum with inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. FITOTERAPIA, 2014, vol. 95, p. 51–57. DOI: 10.1016/j.fitote.2014.02.015. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% ethanol
Substance:

neolignans (RF-00004386-PAR)
Additional substance description:

2,2′-dihydroxy-3-methoxy-1,1′-neolignan
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, FAB-MS, HRESIMS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Neolignans (2,2′-dihydroxy-3-methoxy-1,1′-neolignan)

Composition #20: Gui, Xuan., Wang, Guowei., Zhang, Naidan., Huang, Baokang. New phenylpropanoid and other compounds from Illicium lanceolatum with inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. FITOTERAPIA, 2014, vol. 95, p. 51–57. DOI: 10.1016/j.fitote.2014.02.015. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

Dehydrodieugenol, magnolol)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, FAB-MS, HRESIMS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans (dehydrodieugenol, magnolol)

Composition #21: Gui, Xuan., Wang, Guowei., Zhang, Naidan., Huang, Baokang. New phenylpropanoid and other compounds from Illicium lanceolatum with inhibitory activities against LPS-induced NO production in RAW 264.7 macrophages. FITOTERAPIA, 2014, vol. 95, p. 51–57. DOI: 10.1016/j.fitote.2014.02.015. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% ethanol
Substance:

phenylpropenoids (RF-00010799-PAR)
Additional substance description:

Illicaborin C
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, FAB-MS, HRESIMS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Phenylpropenoids (illicaborin C)