EFSA
ecomole
vscht
  2. Hibiscus rosa-sinensis L.

Hibiscus rosa-sinensis L.

Family:
Malvaceae
Approval state:
Approved
Number of articles retrieved:
1194
Number of processed references:
11
Compositions
#1: Alkaloids #2: Saponins #3: genistein #4: Ononin #5: Isoflavone (4,7-dimetoxyisoflavone) #6: Proanthocyanidins (condensed tannins)
Endpoint Studies
#1: antifertility activity - implantation #2: Antifertility activity connected with β-rosasterol oxide #3: hypoglycemia #4: Hepatotoxicity #5: Nephrotoxicity #6: Biochemical changes in testicular elements and reproduction organs #7: blastocyst implantation failure, antiestrogenic activity #8: strong anti-implantation (inhibition 100%) and uterotropic activities #9: Termination of pregnancy #10: Oestrous cycle prolonged, weights of ovaries and uteri reduced, number of atretic follicles increased #11: abortifacient activity
Genotoxicity
Composition #1: Krishnaiah, D., Devi, T., Bono, A., Sarbatly, R. Studies on phytochemical constituents of six Malaysian medicinal plants. journal of medicinal plants research, 2009, vol. 3, no. 2, p. 067–072. .
Composition #2: Krishnaiah, D., Devi, T., Bono, A., Sarbatly, R. Studies on phytochemical constituents of six Malaysian medicinal plants. journal of medicinal plants research, 2009, vol. 3, no. 2, p. 067–072. .
Composition #3: Aguilar-Urquizo, E., Sangines-Garcia, J. R., Delgadillo, J. A., Capetillo-Leal, C., Torres-Acosta, J. F. J. The onset of puberty of Pelibuey male hair sheep is not delayed by the short term consumption of Morus alba or Hibiscus rosa-sinensis foliage. LIVESTOCK SCIENCE, 2013, vol. 157, no. 1, p. 378–383. DOI: 10.1016/j.livsci.2013.05.031. [DOI link]
Composition #4: Aguilar-Urquizo, E., Sangines-Garcia, J. R., Delgadillo, J. A., Capetillo-Leal, C., Torres-Acosta, J. F. J. The onset of puberty of Pelibuey male hair sheep is not delayed by the short term consumption of Morus alba or Hibiscus rosa-sinensis foliage. LIVESTOCK SCIENCE, 2013, vol. 157, no. 1, p. 378–383. DOI: 10.1016/j.livsci.2013.05.031. [DOI link]
Composition #5: Aguilar-Urquizo, E., Sangines-Garcia, J. R., Delgadillo, J. A., Capetillo-Leal, C., Torres-Acosta, J. F. J. The onset of puberty of Pelibuey male hair sheep is not delayed by the short term consumption of Morus alba or Hibiscus rosa-sinensis foliage. LIVESTOCK SCIENCE, 2013, vol. 157, no. 1, p. 378–383. DOI: 10.1016/j.livsci.2013.05.031. [DOI link]
Composition #6: Aguilar-Urquizo, E., Sangines-Garcia, J. R., Delgadillo, J. A., Capetillo-Leal, C., Torres-Acosta, J. F. J. The onset of puberty of Pelibuey male hair sheep is not delayed by the short term consumption of Morus alba or Hibiscus rosa-sinensis foliage. LIVESTOCK SCIENCE, 2013, vol. 157, no. 1, p. 378–383. DOI: 10.1016/j.livsci.2013.05.031. [DOI link]
Endpoint study #1: Kholkute, S. D., Mudgal, V., Deshpande, P. J. Screening of indigenous medicinal plants for antifertility potentiality. Planta Medica, 1976, p. 151–155. .
Endpoint study #2: Zhou, Mingdong., Jiang, Yan., Zhao, Cuilan., Li, Kaiyuan. Study of antifertility agent in petroleum extract of Hibiscus rosasinensis L. flower. yunnan daxue xuebao, ziran kexueban, 1998, p. 170–171. .
Endpoint study #3: Patel, D.K., Prasad, S.K., Kumar, R., Hemalatha, S. An overview on antidiabetic medicinal plants having insulin mimetic property. Asian Pacific Journal of Tropical Biomedicine, 2012, vol. 2, no. 4, p. 320–330. DOI: 10.1016/S2221-1691(12)60032-X. [DOI link]
Endpoint study #4: Nath Purobi., Yadav Arun K. Acute and sub-​acute oral toxicity assessment of the methanolic extract from leaves of Hibiscus rosa-​sinensis L. in mice. Journal of intercultural ethnopharmacology, 2015, p. 70–73. .
Endpoint study #5: Nath Purobi., Yadav Arun K. Acute and sub-​acute oral toxicity assessment of the methanolic extract from leaves of Hibiscus rosa-​sinensis L. in mice. Journal of intercultural ethnopharmacology, 2015, p. 70–73. .
Endpoint study #6: Kamal, R., Gupta, RS., Lohiya, NK. Plants for male fertility regulation. PHYTOTHERAPY RESEARCH, 2003, vol. 17, no. 6, p. 579–590. DOI: 10.1002/ptr.1320. [DOI link]
Endpoint study #7: Nivsarkar, M., Patel, M., Padh, H., Bapu, C., Shrivastava, N. Blastocyst implantation failure in mice due to "nonreceptive endometrium": endometrial alterations by Hibiscus rosa-sinensis leaf extract. CONTRACEPTION, 2005, vol. 71, no. 3, p. 227–230. DOI: 10.1016/j.contraception.2004.10.004. [DOI link]
Endpoint study #8: Kumar, Dinesh., Kumar, Ajay., Prakash, Om. Potential antifertility agents from plants: A comprehensive review. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 140, no. 1, p. 1–32. DOI: 10.1016/j.jep.2011.12.039. [DOI link]
Endpoint study #9: Kumar, Dinesh., Kumar, Ajay., Prakash, Om. Potential antifertility agents from plants: A comprehensive review. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 140, no. 1, p. 1–32. DOI: 10.1016/j.jep.2011.12.039. [DOI link]
Endpoint study #10: Tung Thanh Tran., Hinds, Lyn A. Fertility control of rodent pests: a review of the inhibitory effects of plant extracts on ovarian function. PEST MANAGEMENT SCIENCE, 2012, vol. 69, no. 3, p. 342–354. DOI: 10.1002/ps.3354. [DOI link]
Endpoint study #11: NATH, D., SETHI, N., SINGH, RK., JAIN, AK. COMMONLY USED INDIAN ABORTIFACIENT PLANTS WITH SPECIAL REFERENCE TO THEIR TERATOLOGIC EFFECTS IN RATS. JOURNAL OF ETHNOPHARMACOLOGY, 1992, vol. 36, no. 2, p. 147–154. DOI: 10.1016/0378-8741(92)90015-J. [DOI link]