EFSA Compendium of Botanicals

Draft - work in progress

Jerusalem artichoke (as plant) // Helianthus tuberosus L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 2508
Number of processed references:: 6

Compositions

#1: Calcium oxalate #2: Coumarins #3: Gallic acid #4: Umbelliferone #5: Salicylic acid #6: Scopoletin #7: p-coumaric acid #8: Sesquiterpene lactones #9: Esculetin #10: Umbelliferone #11: Lectins

Endpoint Studies

Genotoxicity

Composition #1: Meric, Ciler., Dane, Feruzan. Calcium oxalate crystals in floral organs of Helianthus annulus L. and H-tuberosus L. (Asteraceae) . acta biologica szegediensis, 2004, vol. 48, no. 1-4, p. 19–23. .

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Substance:

Calcium oxalate (RF-00003960-PAR)
Analytical method code:

Electron microscopical tests (F096A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Calcium oxalate

Composition #2: Cabello-Hurtado, F., Durst, F., Jorrin, JV., Werck-Reichhart, D. Coumarins in Helianthus tuberosus: Characterization, induced accumulation and biosynthesis. PHYTOCHEMISTRY, 1998, vol. 49, no. 4, p. 1029–1036. DOI: 10.1016/S0031-9422(97)01036-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

ayapin
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

TLC, GC-MC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins

Composition #3: Tchone, M., Baerwald, G., Annemueller, G., Fleischer, L. -G. Separation and identification of phenolic compounds in Jerusalem artichoke (Helianthus tuberosus L.) . sciences des aliments, 2006, vol. 26, no. 5, p. 394–408. DOI: 10.3166/sda.26.394-408. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

gallic acid (RF-00003821-PAR)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1-14.0
Internal remarks:

Gallic acid

Composition #4: Tchone, M., Baerwald, G., Annemueller, G., Fleischer, L. -G. Separation and identification of phenolic compounds in Jerusalem artichoke (Helianthus tuberosus L.) . sciences des aliments, 2006, vol. 26, no. 5, p. 394–408. DOI: 10.3166/sda.26.394-408. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

umbelliferone (RF-00004096-PAR)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2-11.0
Internal remarks:

Umbelliferone

Composition #5: Tchone, M., Baerwald, G., Annemueller, G., Fleischer, L. -G. Separation and identification of phenolic compounds in Jerusalem artichoke (Helianthus tuberosus L.) . sciences des aliments, 2006, vol. 26, no. 5, p. 394–408. DOI: 10.3166/sda.26.394-408. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

Salicylic acid (RF-00000241-VET)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.0-700
Internal remarks:

Salicylic acid

Composition #6: Tchone, M., Baerwald, G., Annemueller, G., Fleischer, L. -G. Separation and identification of phenolic compounds in Jerusalem artichoke (Helianthus tuberosus L.) . sciences des aliments, 2006, vol. 26, no. 5, p. 394–408. DOI: 10.3166/sda.26.394-408. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

scopoletin (RF-00004048-PAR)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1-8.0
Internal remarks:

Scopoletin

Composition #7: Tchone, M., Baerwald, G., Annemueller, G., Fleischer, L. -G. Separation and identification of phenolic compounds in Jerusalem artichoke (Helianthus tuberosus L.) . sciences des aliments, 2006, vol. 26, no. 5, p. 394–408. DOI: 10.3166/sda.26.394-408. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

p-coumaric acid (RF-00010717-PAR)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1-4
Internal remarks:

p-coumaric acid

Composition #8: Yuan, Xiaoyan., Cheng, Mengchun., Gao, Mingzhe., Zhuo, Rongjie., Zhang, Liangxiao., Xiao, Hongbin. Cytotoxic constituents from the leaves of Jerusalem artichoke (Helianthus tuberosus L.) and their structure-activity relationships. PHYTOCHEMISTRY LETTERS, 2013, vol. 6, no. 1, p. 21–25. DOI: 10.1016/j.phytol.2012.10.007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

EtOAc
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

11 sesquiterpene lactones reported
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Sesquiterpene lactones

Composition #9: Bajerova, Petra., Adam, Martin., Bajer, Tomas., Ventura, Karel. Comparison of various techniques for the extraction and determination of antioxidants in plants. JOURNAL OF SEPARATION SCIENCE, 2014, vol. 37, no. 7, p. 835–844. DOI: 10.1002/jssc.201301139. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Esculetin (RF-00003667-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Result unit:

Microgram/100 gram (G046A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.2-15.1
Internal remarks:

Esculetin

Composition #10: Bajerova, Petra., Adam, Martin., Bajer, Tomas., Ventura, Karel. Comparison of various techniques for the extraction and determination of antioxidants in plants. JOURNAL OF SEPARATION SCIENCE, 2014, vol. 37, no. 7, p. 835–844. DOI: 10.1002/jssc.201301139. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Result unit:

Microgram/100 gram (G046A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.9-207.1
Internal remarks:

Umbelliferone

Composition #11: Nakagawa, R., Yasokawa, D., Ikeda, T., Nagashima, K. Purification and characterization of two lectins from callus of Helianthus tuberosus. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1996, vol. 60, no. 2, p. 259–262. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Lectins (RF-00000439-ORG)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lectins