EFSA Compendium of Botanicals

Draft - work in progress

Heimia salicifolia (Kunth) Link

Family:: Lythraceae
Approval state:: Approved
Number of articles retrieved:: 81
Number of processed references:: 1

Compositions

Endpoint Studies

Genotoxicity

Composition #1: Kempf, Juergen., Stedtler, Uwe., Neusuess, Christian., Weinmann, Wolfgang., Auwaerter, Volker. Identification of sinicuichi alkaloids in human serum after intoxication caused by oral intake of a Heimia salicifolia extract. FORENSIC SCIENCE INTERNATIONAL, 2008, vol. 179, no. 2-3, p. E57–E61. DOI: 10.1016/j.forsciint.2008.05.009. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Quinolizidine alkaloids (RF-00004327-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Quinolizidine alkaloids

Endpoint study #1: Kempf, Juergen., Stedtler, Uwe., Neusuess, Christian., Weinmann, Wolfgang., Auwaerter, Volker. Identification of sinicuichi alkaloids in human serum after intoxication caused by oral intake of a Heimia salicifolia extract. FORENSIC SCIENCE INTERNATIONAL, 2008, vol. 179, no. 2-3, p. E57–E61. DOI: 10.1016/j.forsciint.2008.05.009. [DOI link]

Study relevance:

Human health
Substance:

Quinolizidine alkaloids (RF-00004327-PAR)
Type of toxicological test:

case report (CHD060TT)
Limit test:

Not applicable
Tested organism:

Human (as organism) (A056J)
Sex:

Male
Route of exposure:

ORAL: DRINKING WATER (OECD2229PL)
Control groups used:

no
Endpoint measured:

Dose not reported (CHD066EP)
Critical effect:

NEUROTOXICITY (TOX04A)
Target tissue:

neurologic: Brain (TT034A)
Effect description:

exhilarating feelings,alteration of awareness, bradycardia, relaxation of the muscles and pleasant faintness
Effect or parameter linked to the endpoint:

neurology (CHD027BE)
Internal remarks:

psychoactive