EFSA Compendium of Botanicals

Draft - work in progress

White ginger (as plant) // Hedychium coronarium J.König

Family:: Zingiberaceae
Approval state:: Approved
Number of articles retrieved:: 304
Number of processed references:: 8

Compositions

#1: Saponins #2: Tannins #3: Eugenol #4: Methyl Salicylate (roots) #5: Eugenol #6: Methyl Salicylate (leaves) #7: Diosgenin #8: Diosgenin #9: 1,8-cineole #10: Saponins #11: Cardiac glycosides #12: Tannins #13: hedychilactones A, B, C #14: Labdane diterpenes #15: Diterpenes (coronarin A, B, C, D)

Endpoint Studies

Genotoxicity

Composition #1: Worthley, Elmer G., Schott, C. Donald. Biologically-active compounds in some flowering plants. life sciences, 1969, p. 225–238. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol and water extractions
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #2: Worthley, Elmer G., Schott, C. Donald. Biologically-active compounds in some flowering plants. life sciences, 1969, p. 225–238. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Stem, leaves and root samples used in ethanol and water extractions
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #3: Haggag, M. Y., El-Shamy, A. M. Phytochemical study of Alpinia nutans (Roscoe) and Hedychium coronarium (Koenig). egyptian journal of pharmaceutical sciences, 1980, p. 465–476. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Eugenol

Composition #4: Haggag, M. Y., El-Shamy, A. M. Phytochemical study of Alpinia nutans (Roscoe) and Hedychium coronarium (Koenig). egyptian journal of pharmaceutical sciences, 1980, p. 465–476. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyl salicylate (RF-00003930-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Methyl Salicylate (roots)

Composition #5: Haggag, M. Y., El-Shamy, A. M. Phytochemical study of Alpinia nutans (Roscoe) and Hedychium coronarium (Koenig). egyptian journal of pharmaceutical sciences, 1980, p. 465–476. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Eugenol

Composition #6: Haggag, M. Y., El-Shamy, A. M. Phytochemical study of Alpinia nutans (Roscoe) and Hedychium coronarium (Koenig). egyptian journal of pharmaceutical sciences, 1980, p. 465–476. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyl salicylate (RF-00003930-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Methyl Salicylate (leaves)

Composition #7: Carabot Cuervo, Alfredo., Usubillaga, Alfredo. New sources of diosgenin in Venezuelan plants. I. revista latinoamericana de quimica, 1981, p. 132–134. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Substance:

Diosgenin (RF-00004094-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

Chromatography + NMR (270 MHz) + IR + MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Diosgenin

Composition #8: Carabot Cuervo, Alfredo., Usubillaga, Alfredo. New sources of diosgenin in Venezuelan plants. I. revista latinoamericana de quimica, 1981, p. 132–134. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Substance:

Diosgenin (RF-00004094-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

Chromatography + NMR (270 MHz) + IR + MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Diosgenin

Composition #9: Lechat-Vahirua, Isabelle., Francois, Patrice., Menut, Chantal., Lamaty, Gerard., Bessiere, Jean-Marie. Aromatic plants of French Polynesia. I. Constituents of the essential oils of rhizomes of three Zingiberaceae: Zingiber zerumbet Smith, Hedychium coronarium Koenig and Etlingera cevuga Smith. Journal of Essential Oil Research, 1993, vol. 5, no. 1, p. 55–59. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

40.2
Internal remarks:

1,8-cineole

Composition #10: Lemino Singh, K., Bag, G.C. Phytochemical analysis and determination of total phenolics content in water extracts of three species of hedychium. International Journal of PharmTech Research, 2013, vol. 5, no. 4, p. 1516–1521. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Distilled water
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #11: Lemino Singh, K., Bag, G.C. Phytochemical analysis and determination of total phenolics content in water extracts of three species of hedychium. International Journal of PharmTech Research, 2013, vol. 5, no. 4, p. 1516–1521. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Distilled water
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardiac glycosides

Composition #12: Lemino Singh, K., Bag, G.C. Phytochemical analysis and determination of total phenolics content in water extracts of three species of hedychium. International Journal of PharmTech Research, 2013, vol. 5, no. 4, p. 1516–1521. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Distilled water
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #13: Matsuda, H., Morikawa, T., Sakamoto, Y., Toguchida, I., Yoshikawa, M. Labdane-type diterpenes with inhibitory effects on increase in vascular permeability and nitric oxide production from Hedychium coronarium. BIOORGANIC & MEDICINAL CHEMISTRY, 2002, vol. 10, no. 8, p. 2527–2534. DOI: 10.1016/S0968-0896(02)00121-9. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

labdane diterpenes (RF-00004392-PAR)
Additional substance description:

hedychilactones A, B, C
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

reversed-phase silica gel column chromatography and HPLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

hedychilactones A, B, C

Composition #14: Suresh, G., Reddy, P. Prabhakar., Babu, K. Suresh., Shaik, Thokhir Basha., Kalivendi, Shasi Vardhan. Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, vol. 20, no. 24, p. 7544–7548. DOI: 10.1016/j.bmcl.2010.09.024. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

hexane
Substance:

labdane diterpenes (RF-00004392-PAR)
Additional substance description:

[6-oxo-7,11,13- labdatrien-17-al-16,15-olide] and [7,17-dihydroxy-6-oxo-7,11,13-labdatrien-16,15-olide]
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Labdane diterpenes

Composition #15: ITOKAWA, H., MORITA, H., KATOU, I., TAKEYA, K., CAVALHEIRO, AJ., DEOLIVEIRA, RCB., ISHIGE, M., MOTIDOME, M. CYTO-TOXIC DITERPENES FROM THE RHIZOMES OF HEDYCHIUM-CORONARIUM. PLANTA MEDICA, 1988, no. 4, p. 311–315. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

hot CHCl3
Substance:

Diterpenes Diterpenes (RF-00004378-PAR)
Additional substance description:

Coronarin A, B, C, D
Analytical method code:

Element spectroscopy (F051A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Diterpenes (coronarin A, B, C, D)