EFSA Compendium of Botanicals

Draft - work in progress

Hebeclinium macrophyllum (L.) DC. // Eupatorium macrophyllum L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 8
Number of processed references:: 2

Compositions

#1: Myrcene in aerial part essential oil #2: Epoxides in the aerial parts

Endpoint Studies

Genotoxicity

Composition #1: Maia, JGS., Zoghbi, MDB., Andrade, EHA., da Silva, MHL., Luz, AIR., da Silva, JD. Essential oils composition of Eupatorium species growing wild in the Amazon. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2002, vol. 30, no. 11, p. 1071–1077. DOI: 10.1016/S0305-1978(02)00059-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distillation, water
Substance:

myrcene (RF-00003503-PAR)
Additional substance description:
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.3
Internal remarks:

Myrcene in aerial part essential oil

Composition #2: WARNING, U., JAKUPOVIC, J., FRIEDRICH, D., CASTRO, V., BOHLMANN, F. FURTHER SECO-LABDANES FROM HEBECLINIUM-MACROPHYLLUM. PHYTOCHEMISTRY, 1987, vol. 26, no. 8, p. 2331-2335. DOI: 10.1016/S0031-9422(00)84713-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

merhanol, ethanol, petrol
Substance:

epoxides (RF-00010829-PAR)
Additional substance description:

caryophyllen-1,10-epoxide: 9-angeloyloxy-10,11-epoxy-4,5-dehydronerolidol
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Epoxides in the aerial parts