EFSA
ecomole
vscht
  2. Jiaogulan (as plant) // Gynostemma pentaphyllum (Thunb.) Makino

Jiaogulan (as plant) // Gynostemma pentaphyllum (Thunb.) Makino

Family:
Cucurbitaceae
Approval state:
Approved
Number of articles retrieved:
2364
Number of processed references:
5
Compositions
#1: Dammarane saponins, gypenosides or gynosaponins. #2: Gypenoside XLIX (dammarane -type saponin) #3: Saponins (total) #4: Gypenosides (saponins) #5: Furan derivatives
Endpoint Studies
#1: In vitro inhibition of pancreatic alpha-amylase and intestinal alpha-glucosidase #2: Alpha-glucosidase inhibition caused by flavonoids
Genotoxicity
Composition #1: Chin, Hao-Chen., Chen, Ying-Chun., Chang, Long-Zen. Analysis of Gypenoside Content in Taiwan native Gynostemma pentaphyllum (Thunb.) Makino and Toxicity Test of a Health Product Use Thereof . bulletin of taichung district agricultural improvement station, 2009, no. 105, p. 23–32. .
Composition #2: Huang, Tom Hsun-Wei., Tran, Van Hoan., Roufogalis, Basil D., Li, Yuhao. Gypenoside XLIX, a naturally occurring gynosaponin, PPAR-alpha dependently inhibits LPS-induced tissue factor expression and activity in human THP-1 monocytic cells . toxicology and applied pharmacology, 2007, vol. 218, no. 1, p. 30–36. DOI: 10.1016/j.taap.2006.10.013. [DOI link]
Composition #3: Chiranthanut, Natthakarn., Teekachunhatean, Supanimit., Panthong, Ampai., Khonsung, Parirat., Kanjanapothi, Duangta., Lertprasertsuk, Nirush. Toxicity evaluation of standardized extract of Gynostemma pentaphyllum Makino . journal of ethnopharmacology, 2013, vol. 149, no. 1, p. 228–234. DOI: 10.1016/j.jep.2013.06.027. [DOI link]
Composition #4: Chiranthanut, Natthakarn., Teekachunhatean, Supanimit., Panthong, Ampai., Khonsung, Parirat., Kanjanapothi, Duangta., Lertprasertsuk, Nirush. Toxicity evaluation of standardized extract of Gynostemma pentaphyllum Makino . journal of ethnopharmacology, 2013, vol. 149, no. 1, p. 228–234. DOI: 10.1016/j.jep.2013.06.027. [DOI link]
Composition #5: Yang, Fei., Shi, Haiming., Zhang, Xiaowei., Yang, Haisha., Zhou, Qin., Yu, Liangli (Lucy). Two new saponins from tetraploid jiaogulan (Gynostemma pentaphyllum), and their anti-inflammatory and alpha-glucosidase inhibitory activities . food chemistry, 2013, vol. 141, no. 4, p. 3606–3613. DOI: 10.1016/j.foodchem.2013.06.015. [DOI link]
Endpoint study #1: Adisakwattana, Sirichai., Jiphimai, Pariwat., Prutanopajai, Pornsawan., Chanathong, Benjanut., Sapwarobol, Suwimol., Ariyapitipan, Tipayanate. Evaluation of alpha-glucosidase, alpha-amylase and protein glycation inhibitory activities of edible plants . international journal of food sciences and nutrition, 2010, vol. 61, no. 3, p. 295–305. DOI: 10.3109/09637480903455963. [DOI link]
Endpoint study #2: Yang, Fei., Shi, Haiming., Zhang, Xiaowei., Yang, Haisha., Zhou, Qin., Yu, Liangli (Lucy). Two new saponins from tetraploid jiaogulan (Gynostemma pentaphyllum), and their anti-inflammatory and alpha-glucosidase inhibitory activities . food chemistry, 2013, vol. 141, no. 4, p. 3606–3613. DOI: 10.1016/j.foodchem.2013.06.015. [DOI link]