Endpoint study
#1: Mahomoodally M Fawzi., Subratty A Hussein., Gurib-Fakim A., Choudhary M Iqbal., Nahar Khan S. Traditional medicinal herbs and food plants have the potential to inhibit key carbohydrate hydrolyzing enzymes in vitro and reduce postprandial blood glucose peaks in vivo. thescientificworldjournal, 2012 . .
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Study relevance:
Human health
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Plant part:
Leaves (as part-nature) (A0EKT)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
various types of extracts
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Type of toxicological test:
in vitro (CHD061TT)
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Endpoint measured:
Enzyme inhibition (CHD067EP)
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Concentration unit:
Microgram/millilitre (G052A)
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Effect concentration:
27.36-384.72
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
alpha-amylase inhibition; range of IC50 depending on the type of extract
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
alpha-amylase inhibition
