EFSA Compendium of Botanicals

Draft - work in progress

Fabiana imbricata Ruiz & Pav.

Family:: Solanaceae
Approval state:: Approved
Number of articles retrieved:: 78
Number of processed references:: 5

Compositions

#1: scopoletin #2: p-hydroxyacetophenone #3: scopoletin #4: Erythroglaucin #5: Physcion #6: scopoletin #7: fabianine #8: scopoletin

Endpoint Studies

Genotoxicity

Composition #1: Schmeda-Hirschmann, G., Jordan, M., Gerth, A., Wilken, D., Hormazabal, E., Tapia, AA. Secondary metabolite content in Fabiana imbricata plants and in vitro cultures. ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES, 2004, vol. 59, no. 1-2, p. 48–54. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane/methanol
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

NMR, micromelting point, co-chromatography with standard samples
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.01-0.56
Internal remarks:

scopoletin

Composition #2: Quispe, Cristina., Viveros-Valdez, Ezequiel., Schmeda-Hirschmann, Guillermo. Phenolic Constituents of the Chilean Herbal Tea Fabiana imbricata R. et P.. PLANT FOODS FOR HUMAN NUTRITION, 2012, vol. 67, no. 3, p. 242–246. DOI: 10.1007/s11130-012-0302-4. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water infusion
Substance:

4-Hydroxyacetophenone (RF-00002341-PAR)
Additional substance description:

p-Hydroxyacetophenone
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

HPLC-DAD, HPLC-ESI-MS/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.4-6.2
Internal remarks:

p-hydroxyacetophenone

Composition #3: Quispe, Cristina., Viveros-Valdez, Ezequiel., Schmeda-Hirschmann, Guillermo. Phenolic Constituents of the Chilean Herbal Tea Fabiana imbricata R. et P.. PLANT FOODS FOR HUMAN NUTRITION, 2012, vol. 67, no. 3, p. 242–246. DOI: 10.1007/s11130-012-0302-4. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water infusion
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Analytical method - additional description:

HPLC-DAD, HPLC-ESI-MS/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.8-1.9
Internal remarks:

scopoletin

Composition #4: KNAPP, JE., THEINER, M., SCHIFF, PL., FARNSWOR.NR. ANTHRAQUINONES AND OTHER CONSTITUENTS OF FABIANA-IMBRICATA. PHYTOCHEMISTRY, 1972, vol. 11, no. 10, p. 3091–&. DOI: 10.1016/0031-9422(72)80120-1. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Erythroglaucin (RF-00010974-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

m.p., m.m.p., UV, IR, MS with an authentic sample and TLC co-chromatography in 3 solvent systems.
Result unit:

Milligram/kilogram (G061A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2
Internal remarks:

Erythroglaucin

Composition #5: KNAPP, JE., THEINER, M., SCHIFF, PL., FARNSWOR.NR. ANTHRAQUINONES AND OTHER CONSTITUENTS OF FABIANA-IMBRICATA. PHYTOCHEMISTRY, 1972, vol. 11, no. 10, p. 3091–&. DOI: 10.1016/0031-9422(72)80120-1. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

physcion (RF-00003993-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

m.p., m.m.p., UV, IR, MS with an authentic sample and TLC co-chromatography in 3 solvent systems.
Result unit:

Milligram/kilogram (G061A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.3
Internal remarks:

Physcion

Composition #6: RAZMILIC, I., SCHMEDAHIRSCHMANN, G., DUTRABEHRENS, M., REYES, S., LOPEZ, I., THEODULOZ, C. RUTIN AND SCOPOLETIN CONTENT AND MICROPROPAGATION OF FABIANA-IMBRICATA. PLANTA MEDICA, 1994, vol. 60, no. 2, p. 140–142. DOI: 10.1055/s-2006-959436. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

NMR
Result unit:

Milligram/100 gram (G057A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

240-2400
Internal remarks:

scopoletin

Composition #7: SCHMEDAHIRSCHMANN, G., PAPASTERGIOU, F. SESQUITERPENES FROM FABIANA-IMBRICATA. PHYTOCHEMISTRY, 1994, vol. 36, no. 6, p. 1439–1442. DOI: 10.1016/S0031-9422(00)89738-1. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol
Substance:

Fabianine (RF-00010937-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

melting point, NMR, MS
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.043
Internal remarks:

fabianine

Composition #8: SCHMEDAHIRSCHMANN, G., PAPASTERGIOU, F. SESQUITERPENES FROM FABIANA-IMBRICATA. PHYTOCHEMISTRY, 1994, vol. 36, no. 6, p. 1439–1442. DOI: 10.1016/S0031-9422(00)89738-1. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

melting point, NMR, MS
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.089
Internal remarks:

scopoletin