Draft - work in progress
-
- Euphorbia lathyris L.
Euphorbia lathyris L.
- Family:
- Euphorbiaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 415
- Number of processed references:
- 3
Composition #1: Hu, Ye., Liang, Hao., Yuan, Qipeng., Hong, Yuancheng. Determination of glucosinolates in 19 Chinese medicinal plants with spectrophotometry and high-pressure liquid chromatography. Natural Product Research, 2010, p. 1195–1205. .
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
Glucosinolates (RF-00000330-TOX)
-
Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
-
Result unit:
Millimole/kilogram (G070A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
6.1
-
Internal remarks:
glucosinolates
Composition #2: Duan, Fei-Peng., Wang, Ying-Zi., Zhang, Chao., Fang, Xin-Sheng., Yan, Bin., Li, Cai-Xia. Chemical composition and biological activity analysis of semen euphorbiae petroleum ether extracts. Journal of Chemical and Pharmaceutical Research, 2014, p. 745–749. .
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol (95%)
-
Substance:
Esculetin (RF-00003667-PAR)
-
Analytical method code:
GC-MS (F046A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
esculetin
Genotox #1: Hassan, A.F., Numan, I.T., Hamad, M.N. Evaluation of genotoxicity and effect of petroleum ether extract of Euphorbia lathyris on bone marrow cells: In-vivo study. International Journal of Pharmaceutical Sciences Review and Research, 2015, vol. 32, no. 2, p. 116–120. .
-
Study category:
Genotoxicity
-
Type of toxicological test:
chromosome aberration assay (CHD047TT)
-
-
Guideline used:
According to
-
Tested organism:
House mouse (as animal) (A0CNT)
-
Strain of test organism:
Swiss (CHD005ST)
-
-
Route of exposure:
OTHER (OECD0PL)
-
Exposure duration for in vivo:
7.0
-
Unit of exposure duration:
Day (G134A)
-
Number of organisms dosed:
24
-
-
Endpoint measured:
chromosome aberration
-
-
Remarks on genotox study:
Petroleum ether extract from seeds caused total chromosomal aberration and decreasing in mitotic index in mice (in vivo)
-
Internal remarks:
Petroleum ether extract from seeds caused total chromosomal aberration and decreasing in mitotic index in mice (in vivo).
-
Internal ID:
eid=2-s2.0-84931834649
