EFSA Compendium of Botanicals

Draft - work in progress

Erysimum cheiranthoides L.

Family:: Brassicaceae
Approval state:: Approved
Number of articles retrieved:: 177
Number of processed references:: 7

Compositions

#1: Cardenolides #2: Erichroside #3: oliroriside #4: Cardenolides (cheiranthosides e+i, strophanthidin) #5: olitoriside #6: cardiac glycosides #7: Glucosinolates (glucocheirolin, glucoiberin) #8: Other present cardenolides #9: Helveticoside #10: Cymarin #11: Cheirotoxin #12: Digitoxigenin #13: Digitoxin #14: erycordin #15: Erysimoside

Endpoint Studies

Genotoxicity

Composition #1: Vysochina, G. I. Quantitative determination of erichroside and total sum of cardenolides in the overground part of Erysimum cheiranthoides L. by the TLC method . rastitel'nye resursy, 1998, vol. 34, no. 1, p. 105–110. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Additional extraction description:

unspecified
Substance:

cardenolides (RF-00004389-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.040-0.550
Internal remarks:

Cardenolides

Composition #2: Vysochina, G. I. Quantitative determination of erichroside and total sum of cardenolides in the overground part of Erysimum cheiranthoides L. by the TLC method . rastitel'nye resursy, 1998, vol. 34, no. 1, p. 105–110. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Additional extraction description:

unspecified
Substance:

Erichroside (RF-00011128-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.010-0.096
Internal remarks:

Erichroside

Composition #3: Buchvarov, I., Butsev, Kh. Extract of cardenolide glycosides from Erysimum cheiranthoides L. seeds and Convallaria majalis L. leaves. farmatsiya (sofia, bulgaria), 1976, p. 9–15. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

olitoriside (RF-00003525-PAR)
Additional substance description:

cardenolides
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

oliroriside

Composition #4: Lei, ZH., Ma, YL., Tai, BS., Jin, ZX., Kong, Q., Yahara, S., Nohara, T. Chemical studies of Erysimum cheiranthoides L. II - Cardenolides from the seeds of Erysimum cheiranthoides. ADVANCES IN PLANT GLYCOSIDES, CHEMISTRY AND BIOLOGY, 1999, vol. 6, p. 403–405. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

cheiranthosides e+i, strophanthidin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

C and H NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardenolides (cheiranthosides e+i, strophanthidin)

Composition #5: Lei, ZH., Kuniyasu, A., Tai, BS., Nakayama, H., Nohara, T. Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides . planta medica, 2001, vol. 67, no. 4, p. 369–370. DOI: 10.1055/s-2001-14309. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

olitoriside (RF-00003525-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

olitoriside

Composition #6: Lei, ZH., Kuniyasu, A., Tai, BS., Nakayama, H., Nohara, T. Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides . planta medica, 2001, vol. 67, no. 4, p. 369–370. DOI: 10.1055/s-2001-14309. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

cheiranthosides I-XI
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cardiac glycosides

Composition #7: HUANG, XP., RENWICK, JAA., SACHDEVGUPTA, K. A CHEMICAL BASIS FOR DIFFERENTIAL ACCEPTANCE OF ERYSIMUM-CHEIRANTHOIDES BY 2 PIERIS SPECIES. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 2, p. 195–210. DOI: 10.1007/BF00993689. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Glucosinolates (RF-00000330-TOX)
Additional substance description:

glucocheirolin, glucoiberin
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Glucosinolates (glucocheirolin, glucoiberin)

Composition #8: SACHDEVGUPTA, K., RADKE, CD., RENWICK, JAA., DIMOCK, MB. CARDENOLIDES FROM ERYSIMUM-CHEIRANTHOIDES - FEEDING DETERRENTS TO PIERIS-RAPAE LARVAE. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 7, p. 1355–1369. DOI: 10.1007/BF00984881. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

Digitoxigenin 3-0- beta-delta-glucoside, Erychroside, Glucodigifucoside, Glucodigigulo methyloside, Strophanthidin
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Other present cardenolides

Composition #9: SACHDEVGUPTA, K., RADKE, CD., RENWICK, JAA., DIMOCK, MB. CARDENOLIDES FROM ERYSIMUM-CHEIRANTHOIDES - FEEDING DETERRENTS TO PIERIS-RAPAE LARVAE. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 7, p. 1355–1369. DOI: 10.1007/BF00984881. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

helveticoside (RF-00003861-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Helveticoside

Composition #10: SACHDEVGUPTA, K., RADKE, CD., RENWICK, JAA., DIMOCK, MB. CARDENOLIDES FROM ERYSIMUM-CHEIRANTHOIDES - FEEDING DETERRENTS TO PIERIS-RAPAE LARVAE. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 7, p. 1355–1369. DOI: 10.1007/BF00984881. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

cymarin (RF-00003761-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cymarin

Composition #11: SACHDEVGUPTA, K., RADKE, CD., RENWICK, JAA., DIMOCK, MB. CARDENOLIDES FROM ERYSIMUM-CHEIRANTHOIDES - FEEDING DETERRENTS TO PIERIS-RAPAE LARVAE. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 7, p. 1355–1369. DOI: 10.1007/BF00984881. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

cheirotoxin (RF-00004203-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cheirotoxin

Composition #12: SACHDEVGUPTA, K., RADKE, CD., RENWICK, JAA., DIMOCK, MB. CARDENOLIDES FROM ERYSIMUM-CHEIRANTHOIDES - FEEDING DETERRENTS TO PIERIS-RAPAE LARVAE. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 7, p. 1355–1369. DOI: 10.1007/BF00984881. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

digitoxigenin (RF-00004273-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Digitoxigenin

Composition #13: SACHDEVGUPTA, K., RADKE, CD., RENWICK, JAA., DIMOCK, MB. CARDENOLIDES FROM ERYSIMUM-CHEIRANTHOIDES - FEEDING DETERRENTS TO PIERIS-RAPAE LARVAE. JOURNAL OF CHEMICAL ECOLOGY, 1993, vol. 19, no. 7, p. 1355–1369. DOI: 10.1007/BF00984881. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

digitoxin (RF-00003778-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Digitoxin

Composition #14: HUANG, XP., RENWICK, JAA. CARDENOLIDES AS OVIPOSITION DETERRENTS TO 2 PIERIS SPECIES - STRUCTURE-ACTIVITY-RELATIONSHIPS. JOURNAL OF CHEMICAL ECOLOGY, 1994, vol. 20, no. 5, p. 1039–1051. DOI: 10.1007/BF02059740. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

cardenolides (RF-00004389-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

erycordin

Composition #15: HUANG, XP., RENWICK, JAA. CARDENOLIDES AS OVIPOSITION DETERRENTS TO 2 PIERIS SPECIES - STRUCTURE-ACTIVITY-RELATIONSHIPS. JOURNAL OF CHEMICAL ECOLOGY, 1994, vol. 20, no. 5, p. 1039–1051. DOI: 10.1007/BF02059740. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Butanol
Substance:

erysimoside (RF-00004290-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Erysimoside