EFSA Compendium of Botanicals

Draft - work in progress

Equisetum telmateia Ehrh.

Family:: Equisetaceae
Approval state:: Approved
Number of articles retrieved:: 140
Number of processed references:: 3

Compositions

#1: Nicotine (alkaloid) #2: Trigonelline (piridininc alkaloid)

Endpoint Studies

Genotoxicity

#1: Higher incidence of micronucleus formation in vitro.

Composition #1: Baytop, Turhan., Gurkan, Elcin. Pharmacognostical investigations on some of the Equisetum species (E.palustre, E. ramosissimum, E. telmateia) of Turkey. journal of faculty of pharmacy of istanbul university, 1972, p. 63–74. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Nicotine (RF-0809-001-PPP)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Nicotine (alkaloid)

Composition #2: Blunden, Gerald., Patel, Asmita., Adrian Romero, Maricela., Guiry, Michael D. Betaines in Four Additional Phyla of Green Plants. natural product communications, 2009, vol. 4, no. 1, p. 101–103. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % methanol
Substance:

trigonelline (RF-00004092-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.01
Internal remarks:

Trigonelline (piridininc alkaloid)

Genotox #1: Milovanović, V., Radulović, N., Todorović, Z., Stanković, M., Stojanović, G. Antioxidant, antimicrobial and genotoxicity screening of hydro-alcoholic extracts of five Serbian Equisetum species. plant foods for human nutrition, 2007, vol. 62, no. 3, p. 113–119. DOI: 10.1007/s11130-007-0050-z. [DOI link]

Study category:

Genotoxicity
Type of toxicological test:

micronucleus assay (CHD051TT)
Method type:

in vitro
Guideline used:

No guideline available
Tested organism:

Human (as organism) (A056J)
Strain of test organism:

lymphocytes (CHD036ST)
Sex:

No data
Exogenous metabolic activation applied:

not applicable
Route of exposure:

OTHER (OECD0PL)
Control groups used:

yes
Endpoint measured:

DNA damage and/or repair
Is genotoxic:

Positive
Remarks on genotox study:

Higher incidence of micronucleus formation in vitro.
Internal remarks:

Higher incidence of micronucleus formation in vitro.
Internal ID:

eid=2-s2.0-34548572758