EFSA Compendium of Botanicals

Draft - work in progress

Equisetum fluviatile L.

Family:: Equisetaceae
Approval state:: Approved
Number of articles retrieved:: 234
Number of processed references:: 2

Compositions

Endpoint Studies

Genotoxicity

#1: Higher incidence of micronucleus formation in vitro.

Composition #1: Radulovic, Niko., Stojanovic, Gordana., Milovanovic, Vesna., Dokovic, Dejan., Randelovic, Vladimir. Volatile constituents of Equisetum fluviatile L.. journal of essential oil research, 2008, vol. 20, no. 5, p. 437–441. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

beta-thujone (RF-00003712-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.9
Internal remarks:

Beta-thujone

Genotox #1: Milovanovic, Vesna., Radulovic, Niko., Todorovic, Zoran., Stankovic, Miroslava., Stojanovic, Gordana. Antioxidant, antimicrobial and genotoxicity screening of hydro-alcoholic extracts of five serbian Equisetum species . plant foods for human nutrition, 2007, vol. 62, no. 3, p. 113–119. DOI: 10.1007/s11130-007-0050-z. [DOI link]

Study category:

Genotoxicity
Type of toxicological test:

micronucleus assay (CHD051TT)
Method type:

in vitro
Guideline used:

No guideline available
Tested organism:

Human (as organism) (A056J)
Strain of test organism:

lymphocytes (CHD036ST)
Sex:

No data
Exogenous metabolic activation applied:

not applicable
Route of exposure:

OTHER (OECD0PL)
Control groups used:

yes
Endpoint measured:

DNA damage and/or repair
Is genotoxic:

Positive
Remarks on genotox study:

Higher incidence of micronucleus formation in vitro.
Internal remarks:

Higher incidence of micronucleus formation in vitro.
Internal ID:

WOS:000249460200005