Composition #1: Melekhova, N. I., Shevlyagina, E. V., Danilova, N. N. Use of an extract of Eleutherococcus spinosus leaves in cosmetics. Maslozhirovaya Promyshlennost, 1972, p. 26–27. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Coumarin (RF-00000370-TOX)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
coumarin
Endpoint study
#1: Melekhova, N. I., Shevlyagina, E. V., Danilova, N. N. Use of an extract of Eleutherococcus spinosus leaves in cosmetics. Maslozhirovaya Promyshlennost, 1972, p. 26–27. .
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Study relevance:
Human health
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Plant part:
Leaves (as part-nature) (A0EKT)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
EtOH
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Type of toxicological test:
not reported (CHD015TT)
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Tested organism:
Human (as organism) (A056J)
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Endpoint measured:
Concentration level (CHD013EP)
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Concentration unit:
International Unit/gram (G252A)
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Effect concentration:
56-80
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Critical effect:
ENDOCRINE (TOX12A)
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Effect description:
estrogen activity
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Effect or parameter linked to the endpoint:
other (CHD003BE)
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Internal remarks:
estrogen activity
