EFSA Compendium of Botanicals

Draft - work in progress

Drimys winteri J.R.Forst. & G.Forst.

Family:: Winteraceae
Approval state:: Approved
Number of articles retrieved:: 277
Number of processed references:: 5

Compositions

#1: gallotannic acid #2: safrole #3: myristicin #4: Eugenol #5: Drimenin #6: sesquiterpene lactones

Endpoint Studies

Genotoxicity

Composition #1: Lemesle, Robert. A complex tannin-resin-protein substance in the bark of Drimys winteri. compt. rend., 1942, p. 237–238. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

tannic acid (RF-00004069-PAR)
Additional substance description:

gallotanic acid
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gallotannic acid

Composition #2: Sierra, Jorge R., Lopez, Jose T., Cortes, Manuel J. (-)-3β-Acetoxydrimenin from the leaves of Drimys winteri. Phytochemistry, 1986, p. 253–254. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petrol
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

safrole

Composition #3: Verdeguer, Mercedes., Garcia-Rellan, David., Boira, Herminio., Perez, Eduardo., Gandolfo, Sandra., Blazquez, Maria Amparo. Herbicidal activity of Peumus boldus and Drimys winterii essential oils from Chile. Molecules, 2011, p. 403–411. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydro distillation, Clevenger-type
Substance:

myristicin (RF-00003941-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.66
Internal remarks:

myristicin

Composition #4: Verdeguer, Mercedes., Garcia-Rellan, David., Boira, Herminio., Perez, Eduardo., Gandolfo, Sandra., Blazquez, Maria Amparo. Herbicidal activity of Peumus boldus and Drimys winterii essential oils from Chile. Molecules, 2011, p. 403–411. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydro distillation, Clevenger-type
Substance:

Eugenol (RF-00003807-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.09
Internal remarks:

Eugenol

Composition #5: Brito, Ivan., Cardenas, Alejandro., Zarraga, Miguel., Paz, Cristian., Perez, Claudia., Lopez-Rodriguez, Matias. X-RAY CRYSTALLOGRAPHIC STRUCTURAL STUDY ON A CINNAMOLIDE-CLASS SESQUITERPENE LACTONE FROM DRIMYS WINTERI FORST. VAR. CHILENSIS. JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2008, vol. 53, no. 4, p. 1732–1733. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichloromethane
Substance:

Drimenin (RF-00010909-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Drimenin

Composition #6: Paz Robles, Cristian., Mercado, Dario., Suarez, Sebastian., Baggio, Ricardo. Two drimane lactones, valdiviolide and 11-epivaldiviolide, in the form of a 1:1 cocrystal obtained from Drimys winteri extracts. ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2014, vol. 70, p. 1112–+. DOI: 10.1107/S205322961402395X. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

valdiviolide, 11-epivaldiviolide
Analytical method - additional description:

X-Ray diffraction
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

sesquiterpene lactones