EFSA Compendium of Botanicals

Draft - work in progress

Dendrobium chrysanthum Wall. ex Lindl.

Family:: Orchidaceae
Approval state:: Approved
Number of articles retrieved:: 92
Number of processed references:: 9

Compositions

#1: Hygrine #2: Alkaloids (cis and trans Dendrochrysine) #3: Alkaloids #4: Emodin #5: Physcion #6: Chrysophanol #7: Lignans #8: Phenanthrene derivative (denchryside A) #9: Alkaloids (cis- and trans-dendrochrysanine) #10: Dendrochrysanene #11: Hygrine

Endpoint Studies

Genotoxicity

Composition #1: Luning, Bjorn., Leander, Kurt. Studies on Orchidaceae alkaloids. III. The alkaloids in Dendrobium primulinum and Dendrobium chrysanthum. acta chemica scandinavica, 1965, p. 1607–1611. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Substance:

Hygrine (RF-00011035-PAR)
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Analytical method - additional description:

NMR, UV, IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Hygrine

Composition #2: Ekevag, Ulf., Elander, Magnus., Gawell, Lars., Leander, Kurt., Luning, Bjorn. Orchidaceae alkaloids. XXXIII. Two new alkaloids, N-cis- and N-trans-cinnamoylnorcuscohygrine from Dendrobium chrysanthum. acta chemica scandinavica, None, p. 1982–1986. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Dendrochrysine (cis- and trans-)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

IR, UV
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids (cis and trans Dendrochrysine)

Composition #3: Huang, Ming-jin., Luo, Chun-li., Zhao, Zhi., Liu, Hong-chang., Wang, Hua-lei., Li, Jin-ling., Luo, Fu-lai. Determination of polysaccharides and total alkaloids in four Caulis dendrobii materials from Xingyi, Guizhou. shizhen guoyi guoyao, 2014, p. 1359–1361. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

acid dye colorimetry
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.41
Internal remarks:

Alkaloids

Composition #4: Yang, L., Wang, Y., Bi, Z.-M., Lin, P., Wang, Z.-T., Xu, L.-S. Studies on chemical constituents of Dendrobium chrysanthum. chinese journal of natural medicines, 2004, vol. 2, no. 5, p. 280–282. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Emodin (RF-00003798-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Emodin

Composition #5: Yang, L., Wang, Y., Bi, Z.-M., Lin, P., Wang, Z.-T., Xu, L.-S. Studies on chemical constituents of Dendrobium chrysanthum. chinese journal of natural medicines, 2004, vol. 2, no. 5, p. 280–282. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

physcion (RF-00003993-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Physcion

Composition #6: Yang, L., Wang, Y., Bi, Z.-M., Lin, P., Wang, Z.-T., Xu, L.-S. Studies on chemical constituents of Dendrobium chrysanthum. chinese journal of natural medicines, 2004, vol. 2, no. 5, p. 280–282. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

chrysophanol (RF-00003737-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Chrysophanol

Composition #7: Ye, QH., Zhao, WM., Qin, GW. Lignans from Dendrobium chrysanthum. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2004, vol. 6, no. 1, p. 39–43. DOI: 10.1080/1028602031000119808. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

Denchryside B; (+)-lyoniresinol; dehydrodiconiferyl alcohol-4-b-D-glucoside; and 7,70 -bis-(4-hydroxy-3,5- dimethoxyphenyl)-8,80 -dihydroxymethyltetrahydrofuran-4b-D-glucoside
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

Column chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans

Composition #8: Ye, QH., Zhao, WM., Qin, GW. New fluorenone and phenanthrene derivatives from Dendrobium chrysanthum. NATURAL PRODUCT RESEARCH, 2003, vol. 17, no. 3, p. 201–205. DOI: 10.1080/1057563021000040817. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Fresh (A166Y)
Additional extraction description:

Ethanol
Substance:

Phenanthrenes (RF-00010826-PAR)
Additional substance description:

Phenanthrene derivative (denchryside A)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

Column chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Phenanthrene derivative (denchryside A)

Composition #9: Yang, L., Zhang, CF., Yang, H., Zhang, M., Wang, ZY., Xu, LS. Two new alkaloids from Dendrobium chrysanthum. HETEROCYCLES, 2005, vol. 65, no. 3, p. 633–636. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

cis- and trans-dendrochrysanine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

Column chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids (cis- and trans-dendrochrysanine)

Composition #10: Yang, L., Qin, LH., Bligh, SWA., Bashall, A., Zhang, CF., Zhang, MA., Wang, ZT., Xu, LS. A new phenanthrene with a spirolactone from Dendrobium chrysanthum and its anti-inflammatory activities . bioorganic & medicinal chemistry, 2006, vol. 14, no. 10, p. 3496–3501. DOI: 10.1016/j.bmc.2006.01.004. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform
Substance:

Phenanthrenes (RF-00010826-PAR)
Additional substance description:

Phenanthrene derivative (Dendrochrysanene)
Analytical method - additional description:

HPLC-PDA-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Dendrochrysanene

Composition #11: EKEVAG, U., ELANDER, M., GAWELL, L., LEANDER, K., LUNING, B. STUDIES ON ORCHIDACEAE ALKALOIDS .33. 2 NEW ALKALOIDS, N-CIS-CINNAMOYLNORCUSKHYGRINE AND N-TRANS-CINNAMOYLNORCUSKHYGRINE FROM DENDROBIUM-CHRYSANTHUM WALL. ACTA CHEMICA SCANDINAVICA, 1973, vol. 27, no. 6, p. 1982–1986. DOI: 10.3891/acta.chem.scand.27-1982. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Hygrine (RF-00011035-PAR)
Additional substance description:

Hygrine and derivatives (N-benzyl-norcuskhygrine; dihydronorcuskhygrine; N-trans-cinnamoyl-dihydronorcuskhygrine)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.33
Internal remarks:

Hygrine