Composition #1: Wang, X., Wei, Q., Zhu, X., Wang, C., Wang, Y., Lin, P., Yang, L. Optimization extracting technology of Cynomorium songaricum Rupr. Saponins by ultrasonic and determination of saponins content in samples with different source. advance journal of food science and technology, 2015, vol. 9, no. 3, p. 209–211. .
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
75% ethanol
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3.69-6.69
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Internal remarks:
Saponins
Composition #2: Ma, Chao-Mei., Sato, Naoto., Li, Xiao-Yu., Nakamura, Norio., Hattori, Masao. Flavan-3-ol contents, anti-oxidative and alpha-glucosidase inhibitory activities of Cynomorium songaricum . food chemistry, 2010, vol. 118, no. 1, p. 116–119. DOI: 10.1016/j.foodchem.2009.04.083.
[
DOI link]
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Plant part:
Stem / stalk (as part-nature) (A067S)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
70% acetone
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Substance:
Tannins (RF-00004337-PAR)
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Additional substance description:
Total tannins (extractable and non-extractable)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
HPLC-MS
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
18.3
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Internal remarks:
Total tannins (extractable and non-extractable)
Endpoint study
#1: Ma, Chao-Mei., Sato, Naoto., Li, Xiao-Yu., Nakamura, Norio., Hattori, Masao. Flavan-3-ol contents, anti-oxidative and alpha-glucosidase inhibitory activities of Cynomorium songaricum . food chemistry, 2010, vol. 118, no. 1, p. 116–119. DOI: 10.1016/j.foodchem.2009.04.083.
[
DOI link]
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Study relevance:
Human health
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Plant part:
Stem / stalk (as part-nature) (A067S)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
g 70% acetone, methanol, water
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Endpoint measured:
Half maximal inhibitory concentration (CHD021EP)
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Concentration unit:
Microgram/millilitre (G052A)
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Effect concentration:
180
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
moderate inhibitory activity on α-glucosidase
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
Inhibition of α-glucosidase activity by stem extract
Endpoint study
#2: Ma, Chao-Mei., Sato, Naoto., Li, Xiao-Yu., Nakamura, Norio., Hattori, Masao. Flavan-3-ol contents, anti-oxidative and alpha-glucosidase inhibitory activities of Cynomorium songaricum . food chemistry, 2010, vol. 118, no. 1, p. 116–119. DOI: 10.1016/j.foodchem.2009.04.083.
[
DOI link]
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Study relevance:
Human health
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Substance:
3-Flavanol (RF-00010876-PAR)
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Additional plant/substance description:
Flavan-3-ol pentamers
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Endpoint measured:
Half maximal inhibitory concentration (CHD021EP)
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Concentration unit:
Microgram/millilitre (G052A)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
inhibitory activity on α-glucosidase
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
Inhibition of α-glucosidase activity by flavan-3-ol pentamers
