EFSA Compendium of Botanicals

Draft - work in progress

Cuscuta europaea L.

Family:: Convolvulaceae
Approval state:: Approved
Number of articles retrieved:: 75
Number of processed references:: 2

Compositions

Endpoint Studies

Genotoxicity

Composition #1: Rohmer, M., Ourisson, G., Benveniste, P., Bimpson, T. Sterol biosynthesis in heterotrophic plant parasites. Phytochemistry, 1975, vol. 14, no. 3, p. 727–730. DOI: 10.1016/0031-9422(75)83022-6. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

sterols, other sterols, other (RF-00000401-NTR)
Additional substance description:

cycloartenol derivatives
Analytical method code:

Mass Spectroscopy and hyphenated methods without chromatography (F063A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cycloartenol derivatives

Endpoint study #1: Breitwieser, K. Native [German] plants and their suitability as laxatives. II. Cuscuta europaea L. (dodder). Deutsche Apotheker Zeitung, 1943, p. 33–34. .

Study relevance:

Human health
Plant part:

Aerial part of plants (as part-nature) (A166F)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

water decoction
Type of toxicological test:

acute toxicity (CHD016TT)
Limit test:

Not applicable
Tested organism:

Rat (as animal) (A0CNV)
Sex:

No data
Route of exposure:

ORAL: UNSPECIFIED (OECD2234PL)
Control groups used:

no data
Endpoint measured:

Dose level (CHD014EP)
Concentration unit:

Grams per kilogram body weight (G226A)
Effect concentration:

0.089
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

catharsis
Effect or parameter linked to the endpoint:

other (CHD003BE)
Internal remarks:

Cathartic