EFSA Compendium of Botanicals

Draft - work in progress

Curcuma aromatica Salisb. // Curcuma wenyujin Y.H.Chen & C.Ling

Family:: Zingiberaceae
Approval state:: Approved
Number of articles retrieved:: 1022
Number of processed references:: 10

Compositions

#1: Beta-myrcene in leaves #2: 1,8-cineole in roots #3: 1,8-cineole in leaves #4: Camphor in roots #5: Camphor in leaves #6: Codonolactone #7: Curcumaromins A to C #8: Furanodiene #9: Curcumrinols A to C #10: Curzerene #11: Curcuminol D and E #12: Furanodiene #13: Curcumin and derivatives #14: Camphor

Endpoint Studies

Genotoxicity

Composition #1: Srivastava, Mahesh., Singh, Narendra., Yadav, Dhiraj., Kumar, Ajay., Rohit., Saxena, Anju. Volatile constituents of essential oil of Curcuma aromatica salisb. natural products: an indian journal, 2009, p. 40–44. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.3-1.76
Internal remarks:

Beta-myrcene in leaves

Composition #2: Srivastava, Mahesh., Singh, Narendra., Yadav, Dhiraj., Kumar, Ajay., Rohit., Saxena, Anju. Volatile constituents of essential oil of Curcuma aromatica salisb. natural products: an indian journal, 2009, p. 40–44. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12.3-14.95
Internal remarks:

1,8-cineole in roots

Composition #3: Srivastava, Mahesh., Singh, Narendra., Yadav, Dhiraj., Kumar, Ajay., Rohit., Saxena, Anju. Volatile constituents of essential oil of Curcuma aromatica salisb. natural products: an indian journal, 2009, p. 40–44. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

21.87-34.01
Internal remarks:

1,8-cineole in leaves

Composition #4: Srivastava, Mahesh., Singh, Narendra., Yadav, Dhiraj., Kumar, Ajay., Rohit., Saxena, Anju. Volatile constituents of essential oil of Curcuma aromatica salisb. natural products: an indian journal, 2009, p. 40–44. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

17.86-27.50
Internal remarks:

Camphor in roots

Composition #5: Srivastava, Mahesh., Singh, Narendra., Yadav, Dhiraj., Kumar, Ajay., Rohit., Saxena, Anju. Volatile constituents of essential oil of Curcuma aromatica salisb. natural products: an indian journal, 2009, p. 40–44. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

11.75-13.94
Internal remarks:

Camphor in leaves

Composition #6: Tao, Z.-M., Li, Y.-Y., Ji, P., Wang, Y.-B., Qin, G.-W. Chemical constituents from aerial part of Curcuma wenyujin. zhongguo zhongyao zazhi, 2007, vol. 32, no. 24, p. 2604–2606. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Additional extraction description:

unspecified
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

Codonolactone
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Codonolactone

Composition #7: Qin, X.-D., Zhao, Y., Gao, Y., Ren, F.-C., Yang, S., Wang, F. Curcumaromins A, B, and C, three novel curcuminoids from Curcuma aromatica. Helvetica Chimica Acta, 2015, vol. 98, no. 9, p. 1325–1331. DOI: 10.1002/hlca.201500080. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Aqueous ethanol
Substance:

Curcumin (RF-00000108-ADD)
Additional substance description:

Curcumin derivatives: Curcumaromins A to C
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

Column chromatography
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Curcumaromins A to C

Composition #8: Yang, FQ., Li, SP., Chen, Y., Lao, SC., Wang, YT., Dong, TTX., Tsim, KWK. Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry . journal of pharmaceutical and biomedical analysis, 2005, vol. 39, no. 3-4, p. 552–558. DOI: 10.1016/j.jpba.2005.05.001. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Furanodiene (RF-00011192-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.12-5.63
Internal remarks:

Furanodiene

Composition #9: Huang, Wei., Zhang, Peng., Jin, Ye-Cheng., Shi, Qiang., Cheng, Yi-Yu., Qu, Hai-Bin., Ma, Zhong-Jun. Cytotoxic diterpenes from the root tuber of Curcuma wenyujin. helvetica chimica acta, 2008, vol. 91, no. 5, p. 944–950. DOI: 10.1002/hlca.200890100. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

labdane diterpenes (RF-00004392-PAR)
Additional substance description:

Curcumrinols A to C
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

LC-MS + NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Curcumrinols A to C

Composition #10: Zhang, J. S., Guan, J., Yang, F. Q., Liu, H. G., Cheng, X. J., Li, S. P. Qualitative and quantitative analysis of four species of Curcuma rhizomes using twice development thin layer chromatography . journal of pharmaceutical and biomedical analysis, 2008, vol. 48, no. 3, p. 1024–1028. DOI: 10.1016/j.jpba.2008.07.006. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

furan derivatives (RF-00004396-PAR)
Additional substance description:

Curzerene
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.43-85.28
Internal remarks:

Curzerene

Composition #11: Zhang, Peng., Huang, Wei., Song, Zhihang., Zhang, Min., Cheng, Lin., Cheng, Yiyu., Qu, Haibin., Ma, Zhongjun. Cytotoxic diterpenes from the radix of Curcuma wenyujin. phytochemistry letters, 2008, vol. 1, no. 2, p. 103–106. DOI: 10.1016/j.phytol.2008.05.001. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

labdane diterpenes (RF-00004392-PAR)
Additional substance description:

Curcuminol D and E
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

HPLC + NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Curcuminol D and E

Composition #12: Zhong, Zhangfeng., Dang, Yuanye., Yuan, Xia., Guo, Wei., Li, Yingbo., Tan, Wen., Cui, Jingrong., Lu, Jinjian., Zhang, Qingwen., Chen, Xiuping., Wang, Yitao. Furanodiene, a Natural Product, Inhibits Breast Cancer Growth Both in vitro and in vivo . cellular physiology and biochemistry, 2012, vol. 30, no. 3, p. 778–790. DOI: 10.1159/000341457. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

furan derivatives (RF-00004396-PAR)
Additional substance description:

Furanodiene
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Furanodiene

Composition #13: Pant, Neerja., Misra, Himanshu., Jain, D. C. Phytochemical investigation of ethyl acetate extract from Curcuma aromatica Salisb. rhizomes . arabian journal of chemistry, 2013, vol. 6, no. 3, p. 279–283. DOI: 10.1016/j.arabjc.2010.10.007. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethylacetate
Substance:

Curcumin (RF-00000108-ADD)
Additional substance description:

Curcumin and derivatives
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Curcumin and derivatives

Composition #14: An, Yue-Wei., Hu, Guang., Yin, Guo-Ping., Zhu, Jing-Jing., Zhang, Qi-Wei., Wang, Zhi-Min., Peng, Juan., Fan, Bin. Quantitative Analysis and Discrimination of Steamed and Non-Steamed Rhizomes of Curcuma wenyujin by GC-MS and HPLC. JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2014, vol. 52, no. 9, p. 961–970. DOI: 10.1093/chromsci/bmt149. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Cyclohexane
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

Chromatographic tests (F015A)
Analytical method - additional description:

GC-MS, HPLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Camphor