EFSA Compendium of Botanicals

Draft - work in progress

Crataegus pinnatifida Bunge

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 1219
Number of processed references:: 3

Compositions

#1: amygdalin (cyanogenic glycoside) #2: Pennatifidanin I-IX and other nine analogues ( neolignans) #3: Lignans

Endpoint Studies

Genotoxicity

Composition #1: Cho, A.-Yeon., Shin, Kum-Joo., Chung, Junho., Oh, Sangsuk. A sensitive enzyme immunoassay for amygdalin in food extracts using a recombinant antibody. journal of food protection, 2008, p. 2048–2052. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

boiling water
Substance:

amygdalin (RF-00003680-PAR)
Analytical method code:

Enzyme Immunoassay Tests (EIA) (F079A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

amygdalin (cyanogenic glycoside)

Composition #2: Huang, Xiao-Xiao., Zhou, Chen-Chen., Li, Ling-Zhi., Li, Fei-Fei., Lou, Li-Li., Li, Dian-Ming., Ikejima, Takshi., Peng, Ying., Song, Shao-Jiang. The cytotoxicity of 8-O-4 ' neolignans from the seeds of Crataegus pinnatifida . bioorganic & medicinal chemistry letters, 2013, vol. 23, no. 20, p. 5599–5604. DOI: 10.1016/j.bmcl.2013.08.045. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% ethanol
Substance:

neolignans (RF-00004386-PAR)
Additional substance description:

8-0-4'- neolignans ( i.e. Pinnatifidanin I-IX) and other nine analogues
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Pennatifidanin I-IX and other nine analogues ( neolignans)

Composition #3: Wu, Jiaqi., Peng, Wei., Qin, Rongxin., Zhou, Hong. Crataegus pinnatifida: Chemical Constituents, Pharmacology, and Potential Applications . molecules, 2014, vol. 19, no. 2, p. 1685–1712. DOI: 10.3390/molecules19021685. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

11 different lignans including shanyenoside A, tortoside A and verbascoside.
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Lignans