Draft - work in progress
-
- Cordia martinicensis (Jacq.) Roem. & Schult.
Cordia martinicensis (Jacq.) Roem. & Schult.
- Family:
- Boraginaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 7
- Number of processed references:
- 2
Composition #1: Martínez Hormaza, Ioanna., Victoria Amador, María del Carmen., Brito Álvarez, Gisselle., Morón Rodríguez, Francisco., López Barreiro, Marisol., García Hernández, Ana Ibis., Duménigo González, Abel., Morejón Rodríguez, Zulema., Bacallao Elguea, Yunier., Nossin, Emmanuel. Preclinical validation of antinociceptive, antiinflammatory, and antipyretic activities of Cordia martinicensis leave decoction . revista cubana de plantas medicinales, 2014, vol. 19, no. 1, p. 29–39. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Additional extraction description:
aqueous extract (decoction)
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
tannins
Composition #2: Martínez Hormaza, Ioanna., Victoria Amador, María del Carmen., Brito Álvarez, Gisselle., Morón Rodríguez, Francisco., López Barreiro, Marisol., García Hernández, Ana Ibis., Duménigo González, Abel., Morejón Rodríguez, Zulema., Bacallao Elguea, Yunier., Nossin, Emmanuel. Preclinical validation of antinociceptive, antiinflammatory, and antipyretic activities of Cordia martinicensis leave decoction . revista cubana de plantas medicinales, 2014, vol. 19, no. 1, p. 29–39. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Drying (dehydration) (A07KG)
-
Additional extraction description:
aqueous extract (decoction)
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
alkaloids
Endpoint study
#1: Rapisarda, A., Barbera, R., De Pasquale, A., Ficarra, P., Ficarra, R., Tommasini, S., Calabro, M.L., Ragusa, S. Cordia francisci, C. martinicensis, C. myxa, C. serratifolia, and C. ulmifolia leaves as new sources of rutin: Analgesic and anti-inflammatory activity. planta medica, 1992, vol. 58, no. 7 SUPPL. . .
-
Study relevance:
Human health
-
Substance:
Pyrrolizidine alkaloids (RF-00000230-TOX)
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Preparation/Extraction method:
Solvent extraction (A0BZR)
-
Additional plant/substance description:
ethanol extract
-
Type of toxicological test:
chronic/long term toxicity (CHD004TT)
-
Tested organism:
Rat (as animal) (A0CNV)
-
Route of exposure:
ORAL: GAVAGE (OECD2231PL)
-
Endpoint measured:
Dose level (CHD014EP)
-
Concentration unit:
Gram/kilogram (G015A)
-
-
Critical effect:
HEPATOTOXICITY (TOX02A)
-
Target tissue:
digestive: Liver (TT023A)
-
Effect description:
hepatotoxicity
-
Effect or parameter linked to the endpoint:
no data (CHD002BE)
-
Internal remarks:
hepatotoxicity
