EFSA Compendium of Botanicals

Draft - work in progress

Clinopodium menthifolium (Host) Stace // Calamintha menthifolia Host.

Family:: Lamiaceae
Approval state:: Approved
Number of articles retrieved:: 10
Number of processed references:: 2

Compositions

#1: Pulegone #2: Piperitone #3: cis-Piperitone oxide #4: trans-Piperitone oxide #5: Piperitenone oxide #6: isopiperitenone #7: pulegone #8: piperitone oxide #9: piperitenone oxide #10: 1,8-cineol

Endpoint Studies

Genotoxicity

Composition #1: Karousou, R., Hanlidou, E., Lazari, D. Essential-oil diversity of three calamintha species from greece. Chemistry and Biodiversity, 2012, vol. 9, no. 7, p. 1364–1372. DOI: 10.1002/cbdv.201100262. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

(+)-pulegone (RF-00003398-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=20.1
Internal remarks:

Pulegone

Composition #2: Karousou, R., Hanlidou, E., Lazari, D. Essential-oil diversity of three calamintha species from greece. Chemistry and Biodiversity, 2012, vol. 9, no. 7, p. 1364–1372. DOI: 10.1002/cbdv.201100262. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

p-Menth-1-en-3-one (RF-00009951-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=10.4
Internal remarks:

Piperitone

Composition #3: Karousou, R., Hanlidou, E., Lazari, D. Essential-oil diversity of three calamintha species from greece. Chemistry and Biodiversity, 2012, vol. 9, no. 7, p. 1364–1372. DOI: 10.1002/cbdv.201100262. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

Cis-Piperitone epoxide (RF-00011465-PAR)
Additional substance description:

cis-Piperitone oxide
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=88.2
Internal remarks:

cis-Piperitone oxide

Composition #4: Karousou, R., Hanlidou, E., Lazari, D. Essential-oil diversity of three calamintha species from greece. Chemistry and Biodiversity, 2012, vol. 9, no. 7, p. 1364–1372. DOI: 10.1002/cbdv.201100262. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

trans-piperitone oxide (RF-00011285-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.4
Internal remarks:

trans-Piperitone oxide

Composition #5: Karousou, R., Hanlidou, E., Lazari, D. Essential-oil diversity of three calamintha species from greece. Chemistry and Biodiversity, 2012, vol. 9, no. 7, p. 1364–1372. DOI: 10.1002/cbdv.201100262. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

Piperitenone oxide (RF-00008725-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.3
Internal remarks:

Piperitenone oxide

Composition #6: HANLIDOU, E., KOKKINI, S., BOSABALIDIS, AM., BESSIERE, JM. GLANDULAR TRICHOMES AND ESSENTIAL OIL CONSTITUENTS OF CALAMINTHA-MENTHIFOLIA (LAMIACEAE). PLANT SYSTEMATICS AND EVOLUTION, 1991, vol. 177, no. 1-2, p. 1726. DOI: 10.1007/BF00937823. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

isopiperitenone (RF-00011284-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.3-0.6
Internal remarks:

isopiperitenone

Composition #7: HANLIDOU, E., KOKKINI, S., BOSABALIDIS, AM., BESSIERE, JM. GLANDULAR TRICHOMES AND ESSENTIAL OIL CONSTITUENTS OF CALAMINTHA-MENTHIFOLIA (LAMIACEAE). PLANT SYSTEMATICS AND EVOLUTION, 1991, vol. 177, no. 1-2, p. 1726. DOI: 10.1007/BF00937823. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

(+)-pulegone (RF-00003398-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=0.2
Internal remarks:

pulegone

Composition #8: HANLIDOU, E., KOKKINI, S., BOSABALIDIS, AM., BESSIERE, JM. GLANDULAR TRICHOMES AND ESSENTIAL OIL CONSTITUENTS OF CALAMINTHA-MENTHIFOLIA (LAMIACEAE). PLANT SYSTEMATICS AND EVOLUTION, 1991, vol. 177, no. 1-2, p. 1726. DOI: 10.1007/BF00937823. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

piperitone oxide (RF-00011283-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

62.9-67.6
Internal remarks:

piperitone oxide

Composition #9: HANLIDOU, E., KOKKINI, S., BOSABALIDIS, AM., BESSIERE, JM. GLANDULAR TRICHOMES AND ESSENTIAL OIL CONSTITUENTS OF CALAMINTHA-MENTHIFOLIA (LAMIACEAE). PLANT SYSTEMATICS AND EVOLUTION, 1991, vol. 177, no. 1-2, p. 1726. DOI: 10.1007/BF00937823. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

Piperitenone oxide (RF-00008725-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2-2.3
Internal remarks:

piperitenone oxide

Composition #10: HANLIDOU, E., KOKKINI, S., BOSABALIDIS, AM., BESSIERE, JM. GLANDULAR TRICHOMES AND ESSENTIAL OIL CONSTITUENTS OF CALAMINTHA-MENTHIFOLIA (LAMIACEAE). PLANT SYSTEMATICS AND EVOLUTION, 1991, vol. 177, no. 1-2, p. 1726. DOI: 10.1007/BF00937823. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation; Clevenger distillation apparatus
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=0.2
Internal remarks:

1,8-cineol