EFSA Compendium of Botanicals

Draft - work in progress

Cirsium japonicum (Thunb.) Fisch. ex DC.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 338
Number of processed references:: 5

Compositions

#1: Coumaric acid #2: Syringin #3: lignans #4: coumarin #5: polyacetylene derivatives #6: polyacetylene derivatives

Endpoint Studies

Genotoxicity

Composition #1: Zhi Fei., Kong Ling-yi., Peng Si-xun. Studies on the chemical constituents of Cirsium japonicum DC.. yaoxue xuebao, 2003, vol. 38, no. 6, p. 442–447. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Additional extraction description:

unspecified
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumaric acid

Composition #2: Zhi Fei., Kong Ling-yi., Peng Si-xun. Studies on the chemical constituents of Cirsium japonicum DC.. yaoxue xuebao, 2003, vol. 38, no. 6, p. 442–447. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Additional extraction description:

unspecified
Substance:

Eleutheroside B (RF-00011069-PAR)
Additional substance description:

Syringin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Syringin

Composition #3: Lu, Ying., Duan, Shutao., Pan, Jiahu., Yu, Peizhong. Phytochemical investigation of cirsium japonicum DC.. tianran chanwu yanjiu yu kaifa, 2009, p. 563–565. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

tracheloside
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

lignans

Composition #4: Chon, SU., Kim, YM., Lee, JC. Herbicidal potential and quantification of causative allelochemicals from several Compositae weeds . weed research, 2003, vol. 43, no. 6, p. 444–450. DOI: 10.1046/j.0043-1737.2003.00361.x. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol 95%
Substance:

Coumarin (RF-00000370-TOX)
Analytical method code:

HPLC-UV (F021A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

135.6
Internal remarks:

coumarin

Composition #5: Kang, Tae Jin., Moon, Jung Sun., Lee, Sookyeon., Yirn, Dongsool. Polyacetylene Compound from Cirsium japonicum var. ussuriense Inhibits the LPS-Induced Inflammatory Reaction via Suppression of NF-kappa B Activity in RAW 264.7 Cells. BIOMOLECULES & THERAPEUTICS, 2011, vol. 19, no. 1, p. 97–101. DOI: 10.4062/biomolther.2011.19.1.097. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

polyacetylene derivatives polyacetylene derivatives (RF-00004332-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

polyacetylene derivatives

Composition #6: Lai, Wan-Chun., Wu, Yang-Chang., Danko, Balazs., Cheng, Yuan-Bin., Hsieh, Tusty-Jiuan., Hsieh, Chi-Ting., Tsai, Yu-Chi., El-Shazly, Mohamed., Martins, Ana., Hohmann, Judit., Hunyadi, Attila., Chang, Fang-Rong. Bioactive Constituents of Cirsium japonicum var. australe. JOURNAL OF NATURAL PRODUCTS, 2014, vol. 77, no. 7, p. 1624–1631. DOI: 10.1021/np500233t. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol
Substance:

polyacetylene derivatives polyacetylene derivatives (RF-00004332-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

polyacetylene derivatives