EFSA Compendium of Botanicals

Draft - work in progress

Cladanthus mixtus (L.) Chevall. // Anthemis mixta L. // Chamaemelum mixtum (L.) All. // Ormenis mixta (L.) Dumort.

Family:: Compositae (Asteraceae)
Approval state:: Approved
Number of articles retrieved:: 28
Number of processed references:: 5

Compositions

#1: Camphor (RF-00003986-PAR) #2: beta-myrcene #3: pinocarvone (RF-00003547-PAR) #4: 1,8-cineole (RF-00003470-PAR) #5: 3'-Hydroxycorfin #6: Myrcene #7: 1,8-cineole #8: pinocarvone #9: beta - myrcene #10: 2 - pentyl furan #11: 1,8-cineole #12: artemisia ketone #13: Camphor #14: pinocarvone #15: dendrolasin #16: beta-myrcene #17: Camphor #18: 2 - pentylfuran

Endpoint Studies

Genotoxicity

Composition #1: Ainane, T., Elkouali, M., Ainane, A., Talbi, M. Moroccan traditional fragrance based essential oils: Preparation, composition and chemical identification. Der Pharma Chemica, 2014, vol. 6, no. 6, p. 84–89. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

stem distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

21.36
Internal remarks:

Camphor (RF-00003986-PAR)

Composition #2: Ainane, T., Elkouali, M., Ainane, A., Talbi, M. Moroccan traditional fragrance based essential oils: Preparation, composition and chemical identification. Der Pharma Chemica, 2014, vol. 6, no. 6, p. 84–89. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

stem distillation
Substance:

myrcene (RF-00003503-PAR)
Additional substance description:

beta-myrcene
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.76
Internal remarks:

beta-myrcene

Composition #3: Ainane, T., Elkouali, M., Ainane, A., Talbi, M. Moroccan traditional fragrance based essential oils: Preparation, composition and chemical identification. Der Pharma Chemica, 2014, vol. 6, no. 6, p. 84–89. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

stem distillation
Substance:

pinocarvone (RF-00003547-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.24
Internal remarks:

pinocarvone (RF-00003547-PAR)

Composition #4: Ainane, T., Elkouali, M., Ainane, A., Talbi, M. Moroccan traditional fragrance based essential oils: Preparation, composition and chemical identification. Der Pharma Chemica, 2014, vol. 6, no. 6, p. 84–89. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

stem distillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.14
Internal remarks:

1,8-cineole (RF-00003470-PAR)

Composition #5: Engelmeier, D., Hadacek, F., Hofer, O., Lutz-Kutschera, G., Nagl, M., Wurz, G., Greger, H. Antifungal 3-butylisocoumarins from asteraceae-anthemideae. JOURNAL OF NATURAL PRODUCTS, 2004, vol. 67, no. 1, p. 19–25. DOI: 10.1021/np0301339. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol:chlorophorm:water (1:1:1), followed by extraction using chloroform
Substance:

coumarins (RF-00004351-PAR)
Additional substance description:

3'-Hydroxycorfin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, HRMS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

3'-Hydroxycorfin

Composition #6: Darriet, Florent., Bendahou, Mourad., Costa, Jean., Muselli, Alain. Chemical Compositions of the Essential Oils of the Aerial Parts of Chamaemelum mixtum (L.) Alloni. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, vol. 60, no. 6, p. 1494–1502. DOI: 10.1021/jf203872z. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Gram/100 gram (G013A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=3.6
Internal remarks:

Myrcene

Composition #7: Darriet, Florent., Bendahou, Mourad., Costa, Jean., Muselli, Alain. Chemical Compositions of the Essential Oils of the Aerial Parts of Chamaemelum mixtum (L.) Alloni. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, vol. 60, no. 6, p. 1494–1502. DOI: 10.1021/jf203872z. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Gram/100 gram (G013A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.7
Internal remarks:

1,8-cineole

Composition #8: Darriet, Florent., Bendahou, Mourad., Costa, Jean., Muselli, Alain. Chemical Compositions of the Essential Oils of the Aerial Parts of Chamaemelum mixtum (L.) Alloni. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, vol. 60, no. 6, p. 1494–1502. DOI: 10.1021/jf203872z. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

pinocarvone (RF-00003547-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Gram/100 gram (G013A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=1.3
Internal remarks:

pinocarvone

Composition #9: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Additional substance description:

beta - myrcene
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=26.5
Internal remarks:

beta - myrcene

Composition #10: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

2-Pentylfuran (RF-00008482-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.3
Internal remarks:

2 - pentyl furan

Composition #11: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=11.6
Internal remarks:

1,8-cineole

Composition #12: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

artemisia ketone (RF-00004157-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.1
Internal remarks:

artemisia ketone

Composition #13: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=26.8
Internal remarks:

Camphor

Composition #14: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

pinocarvone (RF-00003547-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=5.6
Internal remarks:

pinocarvone

Composition #15: Elouaddari, A., El Amrani, A., Eddine, JJ., Correia, AID., Barroso, JG., Pedro, LG., Figueiredo, AC. Yield and chemical composition of the essential oil of Moroccan chamomile [Cladanthus mixtus (L.) Chevall.] growing wild at different sites in Morocco. FLAVOUR AND FRAGRANCE JOURNAL, 2013, vol. 28, no. 6, p. 360–366. DOI: 10.1002/ffj.3146. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Dendrolasin (RF-00011179-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=3
Internal remarks:

dendrolasin

Composition #16: Anass, E., El Amrani, A., Eddine, JJ. Effect of the Parts of Plant Material (Flowers and Leaves) on Essential Oil Chemical Composition of Ormenis mixta from Morocco. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2015, vol. 18, no. 2, p. 398–408. DOI: 10.1080/0972060X.2014.935022. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydro-distillation
Substance:

myrcene (RF-00003503-PAR)
Additional substance description:

beta-myrcene
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=12.4
Internal remarks:

beta-myrcene

Composition #17: Anass, E., El Amrani, A., Eddine, JJ. Effect of the Parts of Plant Material (Flowers and Leaves) on Essential Oil Chemical Composition of Ormenis mixta from Morocco. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2015, vol. 18, no. 2, p. 398–408. DOI: 10.1080/0972060X.2014.935022. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydro-distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=33
Internal remarks:

Camphor

Composition #18: Anass, E., El Amrani, A., Eddine, JJ. Effect of the Parts of Plant Material (Flowers and Leaves) on Essential Oil Chemical Composition of Ormenis mixta from Morocco. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2015, vol. 18, no. 2, p. 398–408. DOI: 10.1080/0972060X.2014.935022. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydro-distillation
Substance:

2-Pentylfuran (RF-00008482-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.5- 4.4
Internal remarks:

2 - pentylfuran