EFSA Compendium of Botanicals

Draft - work in progress

Japanese quince (as plant) // Chaenomeles japonica (Thunb.) Lindl. ex Spach

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 130
Number of processed references:: 5

Compositions

#1: Protocatechuic acid #2: Gallic acid #3: Tannins #4: Prunasin #5: p-Coumaric acid #6: 4-Hydroxybenzoic acid

Endpoint Studies

Genotoxicity

Composition #1: Mierina, Inese., Serzane, Rasma., Strele, Maija., Moskaluka, Julija., Ivdre, Elga., Jure, Mara. INVESTIGATION OF THE OIL AND MEAL OF JAPANESE QUINCE (Chaenomeles japonica) SEEDS. and Applied Sciences, 2013, vol. 67, no. 4-5, p. 405–410. DOI: 10.2478/prolas-2013-0071. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

defatted seeds. different extraction methods applied
Substance:

3,4-Dihydroxybenzoic acid (RF-00008853-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.2-46.14
Internal remarks:

Protocatechuic acid

Composition #2: Mierina, Inese., Serzane, Rasma., Strele, Maija., Moskaluka, Julija., Ivdre, Elga., Jure, Mara. INVESTIGATION OF THE OIL AND MEAL OF JAPANESE QUINCE (Chaenomeles japonica) SEEDS. and Applied Sciences, 2013, vol. 67, no. 4-5, p. 405–410. DOI: 10.2478/prolas-2013-0071. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

defatted seeds. different extraction methods applied
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=4.64
Internal remarks:

Gallic acid

Composition #3: Los, Jadwiga., Podsedek, Anna. Tannins from different foodstuffs as trypsin inhibitors. Polish Journal of Food and Nutrition Sciences, 2004, p. 51–55. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Acetone (80%)
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #4: Xu, YN., Kim, JS., Kang, SS., Son, KH., Kim, HP., Chang, HW., Bae, K. A new acylated triterpene from the roots of Chaenomeles japonica. CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, vol. 50, no. 8, p. 1124–1125. DOI: 10.1248/cpb.50.1124. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

prunasin (RF-00004011-PAR)
Additional substance description:

cyanogenic glycoside
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Prunasin

Composition #5: Gornas, Pawel., Siger, Aleksander., Seglina, Dalija. Physicochemical characteristics of the cold-pressed Japanese quince seed oil: New promising unconventional bio-oil from by-products for the pharmaceutical and cosmetic industry. INDUSTRIAL CROPS AND PRODUCTS, 2013, vol. 48, p. 178–182. DOI: 10.1016/j.indcrop.2013.04.018. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (60%)
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

HPLC-UV (F021A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

p-Coumaric acid

Composition #6: Gornas, Pawel., Siger, Aleksander., Seglina, Dalija. Physicochemical characteristics of the cold-pressed Japanese quince seed oil: New promising unconventional bio-oil from by-products for the pharmaceutical and cosmetic industry. INDUSTRIAL CROPS AND PRODUCTS, 2013, vol. 48, p. 178–182. DOI: 10.1016/j.indcrop.2013.04.018. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH (60%)
Substance:

4-Hydroxybenzoic acid (RF-00008325-PAR)
Analytical method code:

HPLC-UV (F021A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

4-Hydroxybenzoic acid

Genotox #1: Pang, Hyung Ae., Lee, Young Wook., Suh, Nan Joo., Chang, Il Moo. Toxicology study on Korean tea materials. Screening of potential mutagenic activities using SOS-chromotest. saengyak hakhoechi, 1990, p. 83–87. .[abstract]

Study category:

Mutagenicity
Type of toxicological test:

SOS/umu test (CHD035TT)
Method type:

in vitro
Guideline used:

No guideline available
Tested organism:

Escherichia coli (as organism) (A0CQA)
Endpoint measured:

DNA damage and/or repair
Is genotoxic:

Positive
Remarks on genotox study:

An ethanolic extract of the fruit was tested. The tested organism is not reported in the paper.
Internal remarks:

SOS-Chromotest positive
Internal ID:

CAPLUS_1991:5000