EFSA Compendium of Botanicals

Draft - work in progress

Cornflower (as plant) // Centaurea cyanus L. // Cyanus segetum Hill.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 724
Number of processed references:: 3

Compositions

#1: Scopoletin #2: Umbelliferone #3: scopoletine #4: umbelliferone #5: umbelliferone #6: scopoletine #7: centcyamine #8: moschamine

Endpoint Studies

Genotoxicity

Composition #1: Bubenchikova, V. N. Coumarins of plants in the genus Centaurea. khimiya prirodnykh soedinenii, 1990, vol. (6), p. 829–30. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% acetone
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Scopoletin

Composition #2: Bubenchikova, V. N. Coumarins of plants in the genus Centaurea. khimiya prirodnykh soedinenii, 1990, vol. (6), p. 829–30. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% acetone
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Umbelliferone

Composition #3: Bubenchikova, V. N. Coumarins of plants in the genus Centaurea. Khimiya Prirodnykh Soedinenii, 1990, p. 829–830. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aceton
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

IR and Raman Spectroscopy (F010A)
Analytical method - additional description:

IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scopoletine

Composition #4: Bubenchikova, V. N. Coumarins of plants in the genus Centaurea. Khimiya Prirodnykh Soedinenii, 1990, p. 829–830. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aceton
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

umbelliferone

Composition #5: Bubenchikova, V. N. Coumarins of plants in the genus Centaurea. Khimiya Prirodnykh Soedinenii, 1990, p. 829–830. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aceton
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

IR and Raman Spectroscopy (F010A)
Analytical method - additional description:

IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

umbelliferone

Composition #6: Bubenchikova, V. N. Coumarins of plants in the genus Centaurea. Khimiya Prirodnykh Soedinenii, 1990, p. 829–830. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aceton
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scopoletine

Composition #7: Sarker, SD., Laird, A., Nahar, L., Kumarasamy, Y., Jaspars, M. Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae). PHYTOCHEMISTRY, 2001, vol. 57, no. 8, p. 1273–1276. DOI: 10.1016/S0031-9422(01)00084-X. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

centcyamine (RF-00011218-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

centcyamine

Composition #8: Sarker, SD., Laird, A., Nahar, L., Kumarasamy, Y., Jaspars, M. Indole alkaloids from the seeds of Centaurea cyanus (Asteraceae). PHYTOCHEMISTRY, 2001, vol. 57, no. 8, p. 1273–1276. DOI: 10.1016/S0031-9422(01)00084-X. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

moschamine (RF-00011220-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

moschamine