EFSA Compendium of Botanicals

Draft - work in progress

Centaurea behen L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 38
Number of processed references:: 5

Compositions

#1: cynaropicrin (sesquterpene lactone) #2: desacylcynaropicrin (sesuiterpene lactone) #3: grosshemin (sesquiterpen lactone) #4: aguirin B (sesquiterpenoid lactone) #5: 3β-O-[α-L-arabinopyranosyl(1→4)-α-L-rhamnopyranosyl(1→ 4)-O-β-D-xylopyranosyl]-16α-hydroxy-13,28-epoxyolean-29-oic acid (triterpene saponins) #6: myrcene #7: solstitialin A #8: Guaianolides

Endpoint Studies

Genotoxicity

Composition #1: Rustaiyan, Abdolhossein., Niknejad, Akram., Zdero, Christa., Bohlmann, Ferdinand. Naturally occurring terpene derivatives. Part 352. A guaianolide from Centaurea behen. Phytochemistry (Elsevier), 1981, p. 2427–2429. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Cynaropicrin (RF-00010896-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cynaropicrin (sesquterpene lactone)

Composition #2: Rustaiyan, Abdolhossein., Niknejad, Akram., Zdero, Christa., Bohlmann, Ferdinand. Naturally occurring terpene derivatives. Part 352. A guaianolide from Centaurea behen. Phytochemistry (Elsevier), 1981, p. 2427–2429. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

desacylcynaropicrin (RF-00011350-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

desacylcynaropicrin (sesuiterpene lactone)

Composition #3: Rustaiyan, Abdolhossein., Niknejad, Akram., Zdero, Christa., Bohlmann, Ferdinand. Naturally occurring terpene derivatives. Part 352. A guaianolide from Centaurea behen. Phytochemistry (Elsevier), 1981, p. 2427–2429. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Grosheimin (RF-00010920-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

grosshemin (sesquiterpen lactone)

Composition #4: Rustaiyan, Abdolhossein., Niknejad, Akram., Zdero, Christa., Bohlmann, Ferdinand. Naturally occurring terpene derivatives. Part 352. A guaianolide from Centaurea behen. Phytochemistry (Elsevier), 1981, p. 2427–2429. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

aguirin B (RF-00010919-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

aguirin B (sesquiterpenoid lactone)

Composition #5: Yadava, R. N., Chakravarti, N. Novel bioactive triterpenoid saponin from Centaurea behen linn. Journal of the Institution of Chemists (India), 2006, p. 135–141. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Drying (dehydration) (A07KG)
Additional extraction description:

3β-O-[α-L-arabinopyranosyl(1→4)-α-L-rhamnopyranosyl(1→ 4)-O-β-D-xylopyranosyl]-16α-hydroxy-13,28-epoxyolean-29-oic acid
Substance:

Triterpene saponins Triterpene saponins (RF-00004338-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

3β-O-[α-L-arabinopyranosyl(1→4)-α-L-rhamnopyranosyl(1→ 4)-O-β-D-xylopyranosyl]-16α-hydroxy-13,28-epoxyolean-29-oic acid (triterpene saponins)

Composition #6: Esmaeili, Akbar., Panahi, Zahra Ali., Ebrahimzadeh, Mohammad Ali. Investigation of Phytochemistry of Gene of Centaurea Grown in Iran. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2014, vol. 17, no. 5, p. 806–812. DOI: 10.1080/0972060X.2014.895203. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

distillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

chem. composition % of essential oil (0,16% in dry aerial part)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.8
Internal remarks:

myrcene

Composition #7: OKSUZ, S., ULUBELEN, A., AYNECHI, Y., WAGNER, H. A GUAIANOLIDE FROM CENTAUREA-BEHEN. PHYTOCHEMISTRY, 1982, vol. 21, no. 11, p. 2747–2749. DOI: 10.1016/0031-9422(82)83116-6. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

solstitialin A (RF-00010916-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

solstitialin A

Composition #8: OKSUZ, S., CLARK, RJ., HERZ, W. A GUAIANOLIDE DIOL MONOACE ATE FROM CENTAUREA-BEHEN AND C-SOLSTITIFLIS SSP SCHOUWII. PHYTOCHEMISTRY, 1993, vol. 33, no. 5, p. 1267–1268. DOI: 10.1016/0031-9422(93)85063-W. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

guaianolides (RF-00010821-PAR)
Analytical method code:

Classification not possible (F001A)
Analytical method - additional description:

X-ray analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Guaianolides