EFSA Compendium of Botanicals

Draft - work in progress

Celosia (as plant) // CEOAR // Celosia argentea L.

Family:: Amaranthaceae
Approval state:: Approved
Number of articles retrieved:: 758
Number of processed references:: 5

Compositions

#1: Oxalic acid #2: Calcium oxalate #3: Dopamine derivatives #4: Betalains #5: Gallic acid #6: p-coumaric acid #7: 4-hydroxybenzaldehyde

Endpoint Studies

#1: alpha-amylase inhibition #2: alpha-glucosidase inhibition

Genotoxicity

Composition #1: Oke, O. L. Chemical changes in some Nigerian vegetables during growth. Experimental Agriculture, 1968, p. 345–349. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Powder (A06JD)
Substance:

oxalic acid (RF-00000356-NTR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.5-12
Internal remarks:

Oxalic acid

Composition #2: Ghorpade, P., Siddiqui, A., Patil, M.J., Rub, R.A. Pharmacognostic and phytochemical evaluation of Celosia argentea. Pharmacognosy Journal, 2012, vol. 4, no. 33, p. 7–15. DOI: 10.5530/pj.2012.33.2. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Substance:

Calcium oxalate (RF-00003960-PAR)
Analytical method code:

Microscopic detection (F536A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Calcium oxalate

Composition #3: Schliemann, W., Cai, YZ., Degenkolb, T., Schmidt, J., Corke, H. Betalains of Celosia argentea. PHYTOCHEMISTRY, 2001, vol. 58, no. 1, p. 159–165. DOI: 10.1016/S0031-9422(01)00141-8. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

dopamine (RF-00000076-NTR)
Additional substance description:

dopamine derivatives
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Dopamine derivatives

Composition #4: Schliemann, W., Cai, YZ., Degenkolb, T., Schmidt, J., Corke, H. Betalains of Celosia argentea. PHYTOCHEMISTRY, 2001, vol. 58, no. 1, p. 159–165. DOI: 10.1016/S0031-9422(01)00141-8. [DOI link]

Language:

English (en)
Plant part:

Flowering top (as part-nature) (A166H)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Betalains (RF-00010820-PAR)
Additional substance description:

amaranthin, betalamic acid
Analytical method code:

HPLC with standard detection methods (F019A)
Result unit:

Millimol/100 Gramm (G193A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0092-0.0622
Internal remarks:

Betalains

Composition #5: Perveen, Shagufta., Yousaf, Muhammad., Zahoor, Ameer Fawad., Rasool, Nasir., Jabber, Abdul. Extraction, isolation, and identification of various environment friendly components from cock's comb (Celosia argentea) leaves for allelopathic potential. TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 2014, vol. 96, no. 10, p. 1523–1534. DOI: 10.1080/02772248.2015.1031457. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aq. Extraction
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Gallic acid

Composition #6: Perveen, Shagufta., Yousaf, Muhammad., Zahoor, Ameer Fawad., Rasool, Nasir., Jabber, Abdul. Extraction, isolation, and identification of various environment friendly components from cock's comb (Celosia argentea) leaves for allelopathic potential. TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 2014, vol. 96, no. 10, p. 1523–1534. DOI: 10.1080/02772248.2015.1031457. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aq. Extraction
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

p-coumaric acid

Composition #7: Perveen, Shagufta., Yousaf, Muhammad., Zahoor, Ameer Fawad., Rasool, Nasir., Jabber, Abdul. Extraction, isolation, and identification of various environment friendly components from cock's comb (Celosia argentea) leaves for allelopathic potential. TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 2014, vol. 96, no. 10, p. 1523–1534. DOI: 10.1080/02772248.2015.1031457. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aq. Extraction
Substance:

4-Hydroxybenzaldehyde (RF-00001976-PAR)
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

4-hydroxybenzaldehyde

Endpoint study #1: Telagari, Madhusudhan., Hullatti, Kirankumar. In-vitro alpha-amylase and alpha-glucosidase inhibitory activity of Adiantum caudatum Linn. and Celosia argentea Linn. extracts and fractions . indian journal of pharmacology, 2015, vol. 47, no. 4, p. 425–429. DOI: 10.4103/0253-7613.161270. [DOI link]

Study relevance:

Human health
Plant part:

Unspecified (A07XD)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

ethanol extract (70% v/v)
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Enzyme inhibition (CHD067EP)
Concentration unit:

Milligram/millilitre (G191A)
Effect concentration:

0.294
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

alpha-amylase inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

alpha-amylase inhibition

Endpoint study #2: Telagari, Madhusudhan., Hullatti, Kirankumar. In-vitro alpha-amylase and alpha-glucosidase inhibitory activity of Adiantum caudatum Linn. and Celosia argentea Linn. extracts and fractions . indian journal of pharmacology, 2015, vol. 47, no. 4, p. 425–429. DOI: 10.4103/0253-7613.161270. [DOI link]

Study relevance:

Human health
Plant part:

Unspecified (A07XD)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

ethanol extract (70% v/v)
Type of toxicological test:

in vitro (CHD061TT)
Endpoint measured:

Enzyme inhibition (CHD067EP)
Concentration unit:

Milligram/millilitre (G191A)
Effect concentration:

0.249
Critical effect:

Digestive (TOX18A)
Target tissue:

Digestive (TT002A)
Effect description:

alpha-glucosidase inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

alpha-glucosidase inhibition