EFSA Compendium of Botanicals

Draft - work in progress

Celastrus paniculatus Willd.

Family:: Celastraceae
Approval state:: Approved
Number of articles retrieved:: 253
Number of processed references:: 5

Compositions

#1: Coumarins #2: Saponins #3: Sesquiterpene alkaloids #4: 4-Hydroxybenzaldehyde #5: Alkaloids #6: Tannins #7: Euonymine #8: Paniculatine A #9: wifornine F #10: Paniculatine B

Endpoint Studies

Genotoxicity

Composition #1: Mohan, Kalaskar G., Sachin, Saner Y., Manohar, Pawar V., Dipak, Rokade L., Sanjay, Surana J. Pharmacognostical Investigation and Physicochemical Analysis of Celastrus paniculatus Willd. Leaves . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 3, p. S1232–S1236. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

coumarins (RF-00004351-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins

Composition #2: Mohan, Kalaskar G., Sachin, Saner Y., Manohar, Pawar V., Dipak, Rokade L., Sanjay, Surana J. Pharmacognostical Investigation and Physicochemical Analysis of Celastrus paniculatus Willd. Leaves . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 3, p. S1232–S1236. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #3: Wagner, H., Heckel, E., Sonnenbichler, J. Structure and stereochemistry of a sesquiterpene ester and three sesquiterpene alkaloids from Celastrus paniculatus. tetrahedron, 1975, p. 1949–1956. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane (alkaloid extract)
Substance:

sesquiterpene alkaloids (RF-00004371-PAR)
Additional substance description:

celapanine, celapanigin, celapagin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Sesquiterpene alkaloids

Composition #4: Lu, Ya-fen., Yang, Shi-lin., Xu, Li-zhen., Chen, He-bin. Chemical constituents of Celastrus paniculatus. zhongcaoyao, 2006, p. 1473–1476. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

4-Hydroxybenzaldehyde (RF-00001976-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

4-Hydroxybenzaldehyde

Composition #5: Debnath, Monojit., Biswas, Moulisha., Shukla, Vinay J., Nishteswar, K. Phytochemical and analytical evaluation of Jyotishmati (Celastrus paniculatus Willd.) leaf extracts. . ayu, 2014, vol. 35, no. 1, p. 54–7. DOI: 10.4103/0974-8520.141929. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Pet. Ether, MeOH, EtOAc
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #6: Debnath, Monojit., Biswas, Moulisha., Shukla, Vinay J., Nishteswar, K. Phytochemical and analytical evaluation of Jyotishmati (Celastrus paniculatus Willd.) leaf extracts. . ayu, 2014, vol. 35, no. 1, p. 54–7. DOI: 10.4103/0974-8520.141929. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #7: Lu, Yasu., Yang, Shilin., Zou, Zhongmei., Luo, Xiuzhen., Chen, Hebin., Xu, Lizhen. Evoninoate sesquiterpene alkaloids from the stem of Celastrus paniculatus . heterocycles, 2006, vol. 68, no. 6, p. 1241–+. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Substance:

Euonymine (RF-00011098-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Euonymine

Composition #8: Lu, Yasu., Yang, Shilin., Zou, Zhongmei., Luo, Xiuzhen., Chen, Hebin., Xu, Lizhen. Evoninoate sesquiterpene alkaloids from the stem of Celastrus paniculatus . heterocycles, 2006, vol. 68, no. 6, p. 1241–+. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Substance:

Paniculatine A (RF-00011393-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Paniculatine A

Composition #9: Lu, Yasu., Yang, Shilin., Zou, Zhongmei., Luo, Xiuzhen., Chen, Hebin., Xu, Lizhen. Evoninoate sesquiterpene alkaloids from the stem of Celastrus paniculatus . heterocycles, 2006, vol. 68, no. 6, p. 1241–+. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Substance:

Wilfornine F (RF-00011395-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

wifornine F

Composition #10: Lu, Yasu., Yang, Shilin., Zou, Zhongmei., Luo, Xiuzhen., Chen, Hebin., Xu, Lizhen. Evoninoate sesquiterpene alkaloids from the stem of Celastrus paniculatus . heterocycles, 2006, vol. 68, no. 6, p. 1241–+. .

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Substance:

Paniculatine B (RF-00011394-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Paniculatine B