Draft - work in progress
-
- Caranda (as plant) // Carissa carandas L.
Caranda (as plant) // Carissa carandas L.
- Family:
- Apocynaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 215
- Number of processed references:
- 6
Composition #1: Gupta, Priti., Bhatnagar, Ira., Kim, Se-Kwon., Verma, Ajay Kumar., Sharma, Anubhuti. In-vitro cancer cell cytotoxicity and alpha amylase inhibition effect of seven tropical fruit residues . asian pacific journal of tropical biomedicine, 2014, vol. 4, no. Suppl. 2, p. S665–S671. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Gravimetric tests (F004A)
-
Result unit:
Gram/100 gram (G013A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
1.96
-
Internal remarks:
Alkaloids (RF-00004360-PAR)
Composition #2: Gupta, Priti., Bhatnagar, Ira., Kim, Se-Kwon., Verma, Ajay Kumar., Sharma, Anubhuti. In-vitro cancer cell cytotoxicity and alpha amylase inhibition effect of seven tropical fruit residues . asian pacific journal of tropical biomedicine, 2014, vol. 4, no. Suppl. 2, p. S665–S671. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
-
Result unit:
Gram/100 gram (G013A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
1.02
-
Internal remarks:
Tannins (RF-00004337-PAR)
Composition #3: Gupta, Priti., Bhatnagar, Ira., Kim, Se-Kwon., Verma, Ajay Kumar., Sharma, Anubhuti. In-vitro cancer cell cytotoxicity and alpha amylase inhibition effect of seven tropical fruit residues . asian pacific journal of tropical biomedicine, 2014, vol. 4, no. Suppl. 2, p. S665–S671. .
-
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Gravimetric tests (F004A)
-
Result unit:
Gram/100 gram (G013A)
-
Result expression:
Dry matter (B002A)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
1.03
-
Internal remarks:
Saponins (RF-00004333-PAR)
Composition #4: Rastogi, R. C., Rastogi, Ram P., Dhar, M. L. Carissa carandas. II. Polar glycosides. indian journal of chemistry, 1967, p. 215–216. .[abstract]
-
-
Substance:
digitoxigenin (RF-00004273-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
digitoxigenin (RF-00004273-PAR)
Composition #5: Zaki, A. Y., El-Tohamy, S. F., El-Fattah, S. A. Study of lipid content and volatile oil of the different organs of Carissa carandas Lin. and Carissa grandiflora Dc. growing in Egypt. egyptian journal of pharmaceutical sciences, 1983, p. 127–141. .[abstract]
-
-
Substance:
myrcene (RF-00003503-PAR)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
myrcene
Composition #6: Mishra, C.K., Shrivastava, B., Sasmal, D. Pharmacognostical standarization and phytochemical identification of fruit and root of Carissa carandas Linn. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL 3, p. 347–350. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponins
Composition #7: Mishra, C.K., Shrivastava, B., Sasmal, D. Pharmacognostical standarization and phytochemical identification of fruit and root of Carissa carandas Linn. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL 3, p. 347–350. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethyl acetate and ethanol
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
alkaloids
Composition #8: Mishra, C.K., Shrivastava, B., Sasmal, D. Pharmacognostical standarization and phytochemical identification of fruit and root of Carissa carandas Linn. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, vol. 5, no. SUPPL 3, p. 347–350. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether, Chloroform, ethyl acetate and ethanol
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
tannins
Composition #9: Siddiqui, BS., Ghani, U., Ali, ST., Usmani, SB., Begum, S. Triterpenoidal constituents of the leaves of Carissa carandas. NATURAL PRODUCT RESEARCH, 2003, vol. 17, no. 3, p. 153–158. DOI: 10.1080/1478641031000104109.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol
-
Substance:
Pentacyclic triterpenic derivatives Pentacyclic triterpenic derivatives (RF-00004309-PAR)
-
Additional substance description:
b-Hydroxy-27-p-E-coumaroyloxyurs-12-en-28-oic acid
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
b-Hydroxy-27-p-E-coumaroyloxyurs-12-en-28-oic acid
Composition #10: Siddiqui, BS., Ghani, U., Ali, ST., Usmani, SB., Begum, S. Triterpenoidal constituents of the leaves of Carissa carandas. NATURAL PRODUCT RESEARCH, 2003, vol. 17, no. 3, p. 153–158. DOI: 10.1080/1478641031000104109.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol
-
Substance:
Pentacyclic triterpenic derivatives Pentacyclic triterpenic derivatives (RF-00004309-PAR)
-
Additional substance description:
carissin
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
carissin
Composition #11: Wangteeraprasert, Ruchira., Likhitwitayawuid, Kittisak. Lignans and a Sesquiterpene Glucoside from Carissa carandas Stem. HELVETICA CHIMICA ACTA, 2009, vol. 92, no. 6, p. 1217–1223. .
-
-
Plant part:
Stem / stalk (as part-nature) (A067S)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
methanol extraction
-
Substance:
lignans (RF-00004361-PAR)
-
Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
lignans (RF-00004361-PAR)
Endpoint study
#1: Gupta, Priti., Bhatnagar, Ira., Kim, Se-Kwon., Verma, Ajay Kumar., Sharma, Anubhuti. In-vitro cancer cell cytotoxicity and alpha amylase inhibition effect of seven tropical fruit residues . asian pacific journal of tropical biomedicine, 2014, vol. 4, no. Suppl. 2, p. S665–S671. .
-
Study relevance:
Human health
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Preparation/Extraction method:
Solvent extraction (A0BZR)
-
Type of toxicological test:
in vitro (CHD061TT)
-
Endpoint measured:
Enzyme inhibition (CHD067EP)
-
Concentration unit:
Milligram/millilitre (G191A)
-
Effect concentration:
29.66
-
Critical effect:
Digestive (TOX18A)
-
Target tissue:
Digestive (TT002A)
-
Effect description:
alpha-amylase inhibition IC50
-
Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
-
Internal remarks:
Alpha-amylase inhibition IC50