EFSA Compendium of Botanicals

Draft - work in progress

Pepper, green (as plant) // Capsicum annuum L. // Capsicum frutescens L.

Family:: Solanaceae
Approval state:: Approved
Number of articles retrieved:: 24768
Number of processed references:: 1

Compositions

Endpoint Studies

Genotoxicity

#1: Capsaicin mutagenic #2: ethanolic extract of the fruit mutagenic in Salmonella TA98. Negative with TA100 and TA1535

Genotox #1: Nagabhushan, M., Bhide, S. V. Mutagenicity of chili extract and capsaicin in short-term tests. environmental mutagenesis, 1985, vol. 7, no. 6, p. 881–8. .

Study category:

Mutagenicity
Type of toxicological test:

bacterial reverse mutation assay (CHD028TT)
Method type:

in vitro
Guideline used:

No guideline followed
Tested organism:

Salmonella typhimurium (as organism) (A0CPZ)
Strain of test organism:

TA 98 (CHD029ST)
Exogenous metabolic activation applied:

with
Control groups used:

yes
Endpoint measured:

gene mutation
Is genotoxic:

Positive
Remarks on genotox study:

Capsaicin mutagenic with Salmonella TA98, as well as with Salmonella TA100 and TA1535
Internal remarks:

Capsaicin mutagenic
Internal ID:

1986:30205

Genotox #2: Nagabhushan, M., Bhide, S. V. Mutagenicity of chili extract and capsaicin in short-term tests. environmental mutagenesis, 1985, vol. 7, no. 6, p. 881–8. .

Study category:

Mutagenicity
Type of toxicological test:

bacterial reverse mutation assay (CHD028TT)
Method type:

in vitro
Guideline used:

No guideline followed
Tested organism:

Salmonella typhimurium (as organism) (A0CPZ)
Strain of test organism:

TA 98 (CHD029ST)
Exogenous metabolic activation applied:

with
Control groups used:

yes
Endpoint measured:

gene mutation
Is genotoxic:

Positive
Remarks on genotox study:

ethanolic extract of the fruit mutagenic in Salmonella TA98. Negative with TA100 and TA1535
Internal remarks:

ethanolic extract of the fruit mutagenic in Salmonella TA98. Negative with TA100 and TA1535
Internal ID:

1986:30205