EFSA Compendium of Botanicals

Draft - work in progress

Canarium luzonicum (Blume) A.Gray

Family:: Burseraceae
Approval state:: Approved
Number of articles retrieved:: 35
Number of processed references:: 2

Compositions

#1: Myrcene #2: methyleugenol #3: elemicin #4: Camphor

Endpoint Studies

Genotoxicity

Composition #1: Clery, Robin. Fragrant adventures in Madagascar. Special Publication - Royal Society of Chemistry, 2002, p. 92–98. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

resin from wounds in the bark
Substance:

myrcene (RF-00003503-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Myrcene

Composition #2: Clery, Robin. Fragrant adventures in Madagascar. Special Publication - Royal Society of Chemistry, 2002, p. 92–98. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

resin from wounds of the bark
Substance:

methyleugenol (RF-00003931-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

methyleugenol

Composition #3: Clery, Robin. Fragrant adventures in Madagascar. Special Publication - Royal Society of Chemistry, 2002, p. 92–98. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

resin from wounds in the bark
Substance:

elemicin (RF-00003787-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

elemicin

Composition #4: Clery, Robin. Fragrant adventures in Madagascar. Special Publication - Royal Society of Chemistry, 2002, p. 92–98. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

resin from wounds in the bark
Substance:

(-)-camphor (RF-00003469-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Camphor

Genotox #1: Lim-Sylianco, C.Y., Shier, W.T. Mutagenic and antimutagenic activities in philippine medicinal and food plants. Toxin Reviews, 1985, vol. 4, no. 1, p. 71–105. DOI: 10.3109/15569548509014414. [DOI link]

Study category:

Mutagenicity
Type of toxicological test:

bacterial gene mutation assay (CHD027TT)
Method type:

in vivo
Tested organism:

Salmonella typhimurium (as organism) (A0CPZ)
Strain of test organism:

TA 1537 (CHD026ST)
Exogenous metabolic activation applied:

with
Endpoint measured:

gene mutation
Is genotoxic:

Positive
Remarks on genotox study:

The oleoresin exhibited significant frame shift mutagenicity (TA1537) only after metabolic activationin the mouse in the host-mediated assay
Internal remarks:

mutagenicity of the oleoresin
Internal ID:

eid=2-s2.0-0022283428