EFSA Compendium of Botanicals

Draft - work in progress

Caesalpinia pulcherrima (L.) Sw.

Family:: Fabaceae
Approval state:: Approved
Number of articles retrieved:: 263
Number of processed references:: 4

Compositions

#1: Myrcene #2: Cardiac glycosides #3: alkaloids #4: Tannins #5: Saponins #6: Coumarins #7: Ellagitanin

Endpoint Studies

Genotoxicity

Composition #1: Usman, L. A., Zubair, M. F., Olawore, N. O., Ashamu, M., Ismaeel, R. O., Oladosu, I. A. Chemical constituents of leaf essential oils of two varieties of Caesalpinia pulcherrima Linn growing in north central Nigeria. elixir online journal, 2012, p. 7085–7087. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.6
Internal remarks:

Myrcene

Composition #2: Sivasankari, K., Janaky, S., Sekar, T. Evaluation of phytochemicals in select medicinal plants of the Caesalpinia species. indian journal of science and technology, 2010, vol. 3, no. 12, p. 1118–1121. DOI: 10.17485/ijst/2010/v3i12/29866. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol, water and petroleum ether
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardiac glycosides

Composition #3: Sivasankari, K., Janaky, S., Sekar, T. Evaluation of phytochemicals in select medicinal plants of the Caesalpinia species. indian journal of science and technology, 2010, vol. 3, no. 12, p. 1118–1121. DOI: 10.17485/ijst/2010/v3i12/29866. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

mehanol,water and petroleum ether
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids

Composition #4: Sivasankari, K., Janaky, S., Sekar, T. Evaluation of phytochemicals in select medicinal plants of the Caesalpinia species. indian journal of science and technology, 2010, vol. 3, no. 12, p. 1118–1121. DOI: 10.17485/ijst/2010/v3i12/29866. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol,chloroform and water
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #5: Sivasankari, K., Janaky, S., Sekar, T. Evaluation of phytochemicals in select medicinal plants of the Caesalpinia species. indian journal of science and technology, 2010, vol. 3, no. 12, p. 1118–1121. DOI: 10.17485/ijst/2010/v3i12/29866. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Chloroform
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #6: Sivasankari, K., Janaky, S., Sekar, T. Evaluation of phytochemicals in select medicinal plants of the Caesalpinia species. indian journal of science and technology, 2010, vol. 3, no. 12, p. 1118–1121. DOI: 10.17485/ijst/2010/v3i12/29866. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

coumarins (RF-00004351-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins

Composition #7: AWASTHI, KK., KUMAR, A., MISRA, K. A NEW TANNIN FROM YOUNG STEM BARK OF CAESALPINIA-PULCHERRIMA. CURRENT SCIENCE, 1980, vol. 49, no. 20, p. 769–772. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Acetone
Substance:

Ellagitannins (hydrolysable tannins) Ellagitannins (hydrolysable tannins) (RF-00004379-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Ellagitanin

Endpoint study #1: Kumar, S., Singh, J., Baghotia, A., Mehta, V., Thakur, V., Choudhary, M., Verma, S., Kumar, D. Antifertility potential of the ethanolic extract of Caesalpinia pulcherrima Linn. leaves. asian pacific journal of reproduction, 2013, vol. 2, no. 2, p. 90–92. DOI: 10.1016/S2305-0500(13)60125-6. [DOI link]

Study relevance:

Human health
Plant part:

Leaves (as part-nature) (A0EKT)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

ethanol 95%
Type of toxicological test:

reproduction toxicity (CHD009TT)
Tested organism:

House mouse (as animal) (A0CNT)
Sex:

Female
Route of exposure:

ORAL: FEED (OECD2230PL)
Exposure duration:

7.0
Unit of exposure duration:

Day (G134A)
Number of organisms dosed:

6
Control groups used:

yes
Endpoint measured:

Dose level (CHD014EP)
Concentration unit:

Milligrams per kilogram body weight (G225A)
Effect concentration:

200-400
Critical effect:

ENDOCRINE (TOX12A)
Target tissue:

urogenital: Uterus (TT052A)
Effect description:

anti-implantation activity
Effect or parameter linked to the endpoint:

reproduction (CHD014BE)
Internal remarks:

anti-implantation activity