EFSA Compendium of Botanicals

Draft - work in progress

Buchanania cochinchinensis (Lour.) M.R.Almeida // Buchanania lanzan Spreng.

Family:: Anacardiaceae
Approval state:: Approved
Number of articles retrieved:: 163
Number of processed references:: 4

Compositions

#1: Vomicine (indole alkaloid) #2: steroidal saponins #3: tannins #4: Alkaloids #5: tannins (fruit)

Endpoint Studies

Genotoxicity

Composition #1: Mehta, Shalini Kapoor., Jaiprakash, B., Nayeem, Naira. Isolation phytochemical investigation on leaves of Buchanania lanzan (Chironji). annals of biological research, 2011, p. 469–473. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

vomicine (RF-00011215-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

MP, IR, LC-MS
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Vomicine (indole alkaloid)

Composition #2: Kodati, D., Pareta, S.K., Patnaik, A. Antidiarrhoeal activity of alcoholic extract of Buchanania lanzan Spreg. Roots. Pharmacologyonline, 2010, vol. 3, p. 720–726. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol and hot temperature
Substance:

steroidal saponins (RF-00010818-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

steroidal saponins

Composition #3: Kodati, D., Pareta, S.K., Patnaik, A. Antidiarrhoeal activity of alcoholic extract of Buchanania lanzan Spreg. Roots. Pharmacologyonline, 2010, vol. 3, p. 720–726. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol and hot temperature
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins

Composition #4: Hullatti, K., Manjunatha, J.R., Kuppasth, I.J. Comparative study on diuretic effect of Buchanania angustifolia Roxb., and Buchanania lanzan Spreng. fruit extracts and fractions. journal of applied pharmaceutical science, 2014, vol. 4, no. 8, p. 59–63. DOI: 10.7324/JAPS.2014.40812. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

90% ethanol an n-hexane
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #5: Hullatti, K., Manjunatha, J.R., Kuppasth, I.J. Comparative study on diuretic effect of Buchanania angustifolia Roxb., and Buchanania lanzan Spreng. fruit extracts and fractions. journal of applied pharmaceutical science, 2014, vol. 4, no. 8, p. 59–63. DOI: 10.7324/JAPS.2014.40812. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

90% ethanol and n-hexane
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins (fruit)

Endpoint study #1: Chaudhary, US., Rathod, V., Vankhede, GN. Effect of water extract of the bark of Buchanania lanzan Linn. on behaviour and chromatophores of a fresh water fish, Labeo rohita. . journal of environmental biology, 2001, vol. 22, no. 3, p. 229–231. .

Study relevance:

Animal (target species) health
Plant part:

Bark (as part-nature) (A066X)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

water extraction
Type of toxicological test:

case report (CHD060TT)
Exposure duration:

96.0
Unit of exposure duration:

Hour (G099A)
Control groups used:

yes
Endpoint measured:

Dose level (CHD014EP)
Concentration unit:

Milligram/litre (G062A)
Effect concentration:

150-550
Critical effect:

NEUROTOXICITY (TOX04A)
Target tissue:

Neurologic (TT004A)
Effect description:

behavior changes( swimming affected, hyperexcitability, spiralling), convulsions, sedative effect (lethargic), death in fish
Effect or parameter linked to the endpoint:

mortality (CHD010BE)
Internal remarks:

neurotoxicity in fish