EFSA Compendium of Botanicals

Draft - work in progress

Bryonia alba L.

Family:: Cucurbitaceae
Approval state:: Approved
Number of articles retrieved:: 163
Number of processed references:: 2

Compositions

#1: Cucurbitacins #2: cucurbitacine B (RF-00004232-PAR) #3: cucurbitacin I

Endpoint Studies

Genotoxicity

Composition #1: Konopa, J., Zielinsky, J., Matuszkiewicz, A. Cucurbitacins, cytotoxic and antitumor substances from Bryonia alba. I. Isolation and identification. arzneimittel-forschung, 1974, p. 1554–1557. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

cucurbitacins (RF-00004352-PAR)
Additional substance description:

Cucurbitacins B, D, E, I, J,K and L; Tetrahydrocucurbitacin I
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cucurbitacins

Composition #2: Toker, G., Erdemoǧlu, N., Toker, M.C. High performance liquid chromatographic analysis of cucurbitacins in some Bryonia species. fabad journal of pharmaceutical sciences, 2000, vol. 25, no. 4, p. 153–156. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol extract, chloroform extract
Substance:

cucurbitacin B (RF-00004232-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result expression:

Dry matter (B002A)
Value (concentration, content):

traces
Internal remarks:

cucurbitacine B (RF-00004232-PAR)

Composition #3: Toker, G., Erdemoǧlu, N., Toker, M.C. High performance liquid chromatographic analysis of cucurbitacins in some Bryonia species. fabad journal of pharmaceutical sciences, 2000, vol. 25, no. 4, p. 153–156. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol extract, chloroform extract
Substance:

cucurbitacin I (RF-00004236-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.0348-0.125
Internal remarks:

cucurbitacin I