Endpoint study
#1: TOKARNIA, CH., GAVA, A., STOLF, L., PEIXOTO, PV. EXPERIMENTAL POISONING IN CATTLE BY BRUNFELSIA-PAUCIFLORA (SOLANACEAE). pesquisa veterinaria brasileira, 1991, vol. 11, no. 1-2, p. 9–12. .
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Study relevance:
Animal (target species) health
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Type of toxicological test:
case report (CHD060TT)
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Tested organism:
Cattle (as animal) (A057E)
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Route of exposure:
ORAL: FEED (OECD2230PL)
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Number of organisms dosed:
11
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Control groups used:
no data
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
NEUROTOXICITY (TOX04A)
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Target tissue:
neurologic: Central Nervous System (TT035A)
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Effect description:
salivation, restlessness, stretching and shaking of hindlegs, excitability and muscular tremors, sudden contractions, lack of stability/ falling, epileptic seizures, loss of appetite/weight, liquid faeces
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Effect or parameter linked to the endpoint:
neurology (CHD027BE)
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Internal remarks:
Neurological effects: salivation, restlessness, stretching and shaking of hindlegs, excitability and muscular tremors, sudden contractions, lack of stability/ falling, epileptic seizures, loss of appetite/weight, liquid faeces
