Draft - work in progress
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- Brunfelsia bonodora (Vell.) J.F.Macbr. // Besleria bondora Vell.
Brunfelsia bonodora (Vell.) J.F.Macbr. // Besleria bondora Vell.
- Family:
- Solanaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 4
- Number of processed references:
- 1
Endpoint study
#1: McBarron EJ., de Sarem W. Letter: Poisoning of dogs by the fruits of the garden shrub Brunfelsia bonodora.. Australian veterinary journal, 1975, vol. 51, no. 5, p. 280-.
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Study relevance:
Animal (target species) health
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Plant part:
Fruit unspecified (as part-nature) (A067D)
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Preparation/Extraction method:
Fresh (A166Y)
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Type of toxicological test:
case report (CHD060TT)
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Tested organism:
Dog (as animal) (A0CNL)
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-
Route of exposure:
ORAL: FEED (OECD2230PL)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
NEPHROTOXICITY (TOX03A)
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Target tissue:
urogenital: Kidneys (TT046A)
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Effect description:
profuse urination with blood
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
nephrotoxicity
Endpoint study
#2: McBarron EJ., de Sarem W. Letter: Poisoning of dogs by the fruits of the garden shrub Brunfelsia bonodora.. Australian veterinary journal, 1975, vol. 51, no. 5, p. 280-.
-
Study relevance:
Animal (target species) health
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Preparation/Extraction method:
Fresh (A166Y)
-
Type of toxicological test:
case report (CHD060TT)
-
Tested organism:
Dog (as animal) (A0CNL)
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-
Route of exposure:
ORAL: FEED (OECD2230PL)
-
-
Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
vomiting, diarrhoea, gastroenteritis
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
profuse salivation, vomiting diarrhoea, gastroenteritis
Endpoint study
#3: McBarron EJ., de Sarem W. Letter: Poisoning of dogs by the fruits of the garden shrub Brunfelsia bonodora.. Australian veterinary journal, 1975, vol. 51, no. 5, p. 280-.
-
Study relevance:
Animal (target species) health
-
Plant part:
Fruit unspecified (as part-nature) (A067D)
-
Preparation/Extraction method:
Fresh (A166Y)
-
Type of toxicological test:
case report (CHD060TT)
-
Tested organism:
Dog (as animal) (A0CNL)
-
-
Route of exposure:
ORAL: FEED (OECD2230PL)
-
-
Endpoint measured:
Dose not reported (CHD066EP)
-
Critical effect:
NEUROTOXICITY (TOX04A)
-
Target tissue:
Muscle, Skeletal (TT055A)
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Effect description:
depression, limbs spasms, staring eyes, involuntary rhythmic movements, tremor and convulsions
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
-
Internal remarks:
neurotoxicity
