EFSA
ecomole
vscht
  2. Brucea antidysenterica J.F.Mill. // Brucea ferruginea L'Hér.

Brucea antidysenterica J.F.Mill. // Brucea ferruginea L'Hér.

Family:
Simaroubaceae
Approval state:
Approved
Number of articles retrieved:
66
Number of processed references:
5
Compositions
#1: 1-Methoxycanthin-6-one #2: Canthin-6-one Alkaloids #3: Bruceantin #4: Quassinoids in bark #5: Bruceanic acids and derivatives #6: quassinoids in stems
Endpoint Studies
Genotoxicity
Composition #1: Fukamiya, Narihiko., Okano, Masayoshi., Aratani, Takaaki., Negoro, Kenji., Lin, Yuh Meei., Lee, Kuo Hsiung. Antitumor agents: LXXXXVII. Cytotoxic antileukemic canthin-​6-​one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Medica, 1987, p. 140–143. .
Composition #2: Fukamiya, Narihiko., Okano, Masayoshi., Aratani, Takaaki., Negoro, Kenji., Lin, Yuh Meei., Lee, Kuo Hsiung. Antitumor agents: LXXXXVII. Cytotoxic antileukemic canthin-​6-​one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Medica, 1987, p. 140–143. .
Composition #3: Cuendet, M., Pezzuto, JM. Antitumor activity of bruceantin: An old drug with new promise. JOURNAL OF NATURAL PRODUCTS, 2004, vol. 67, no. 2, p. 269–272. DOI: 10.1021/np030304+. [DOI link]
Composition #4: KUPCHAN, SM., BRITTON, RW., LACADIE, JA., ZIEGLER, MF., SIGEL, CW. ISOLATION AND STRUCTURAL ELUCIDATION OF BRUCEANTIN AND BRUCEANTINOL, NEW POTENT ANTILEUKEMIC QUASSINOIDS FROM BRUCEA-ANTIDYSENTERICA. JOURNAL OF ORGANIC CHEMISTRY, 1975, vol. 40, no. 5, p. 648–654. DOI: 10.1021/jo00893a023. [DOI link]
Composition #5: TOYOTA, T., FUKAMIYA, N., OKANO, M., TAGAHARA, K., CHANG, JJ., LEE, KH. ANTITUMOR AGENTS .118. THE ISOLATION AND CHARACTERIZATION OF BRUCEANIC ACID-A, ITS METHYL-ESTER, AND THE NEW BRUCEANIC ACID-B, ACID-C, AND ACID-D, FROM BRUCEA-ANTIDYSENTERICA. JOURNAL OF NATURAL PRODUCTS, 1990, vol. 53, no. 6, p. 1526–1532. DOI: 10.1021/np50072a020. [DOI link]
Composition #6: Imamura, K., Fukamiya, N., Nakamura, M., Okano, M., Tagahara, K., Lee, KH. Bruceanols G and H, cytotoxic quassinoids from Brucea antidysenterica. JOURNAL OF NATURAL PRODUCTS, 1995, vol. 58, no. 12, p. 1915–1919. DOI: 10.1021/np50126a019. [DOI link]